Findings

What do systematic reviews say?

1,501 questions · 1,558 findings · 115 reviews · Vascular

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No studies found 346 · 22.2%GRADE not reported 90 · 5.8%Very low 281 · 18%Low 477 · 30.6%Moderate 313 · 20.1%High 51 · 3.3%

Intervention not reported

Early postoperative non‐thrombotic complications · Individuals with peripheral arterial disease

The intervention showed no clear difference in early postoperative non‐thrombotic complications (high certainty).

1 finding from 1 review

Bypass surgery for chronic lower limb ischaemia 2017 · Cochrane Headline outcomes only
OR 1.29 [0.96, 1.73]
6 studies · 1015 participants
High

Intervention not reported

Procedural mortality · Individuals with peripheral arterial disease

The intervention showed no clear difference in procedural mortality (high certainty).

1 finding from 1 review

Bypass surgery for chronic lower limb ischaemia 2017 · Cochrane Headline outcomes only
OR 1.67 [0.66, 4.19]
5 studies · 913 participants
High

Intervention not reported

Clinical improvement · Individuals with peripheral arterial disease

The intervention showed no clear difference in clinical improvement (low certainty).

1 finding from 1 review

Bypass surgery for chronic lower limb ischaemia 2017 · Cochrane Headline outcomes only
OR 0.65 [0.03, 14.52]
2 studies · 154 participants
Low

Intervention not reported

Amputation · Individuals with peripheral arterial disease

The intervention showed no clear difference in amputation (high certainty).

1 finding from 1 review

Bypass surgery for chronic lower limb ischaemia 2017 · Cochrane Headline outcomes only
OR 1.24 [0.82, 1.87]
5 studies · 752 participants
High

Intervention not reported

Primary patency · Individuals with peripheral arterial disease

The intervention probably leads to higher primary patency (moderate certainty).

1 finding from 1 review

Bypass surgery for chronic lower limb ischaemia 2017 · Cochrane Headline outcomes only
OR 1.94 [1.2, 3.14]
4 studies · 300 participants
Moderate

Intervention not reported

Primary patency · Individuals with peripheral arterial disease

The intervention showed no clear difference in primary patency (high certainty).

1 finding from 1 review

Bypass surgery for chronic lower limb ischaemia 2017 · Cochrane Headline outcomes only
OR 1.15 [0.74, 1.78]
2 studies · 363 participants
High

Intervention not reported

Mortality within · Individuals with peripheral arterial disease

The intervention showed no clear difference in mortality within (high certainty).

1 finding from 1 review

Bypass surgery for chronic lower limb ischaemia 2017 · Cochrane Headline outcomes only
OR 0.94 [0.71, 1.25]
5 studies · 961 participants
High

Low molecular weight heparin vs vitamin K antagonist (VKA)

Recurrent VTE · patients with symptomatic VTE requiring long term treatment (3 months) for symptomatic VTE

LMWH showed no clear difference in incidence of recurrent VTE (treatment duration 3 months) compared with VKA (moderate certainty).

1 finding from 1 review

Vitamin K antagonists versus low‐molecular‐weight heparin for the long term treatment of symptomatic venous… 2017 · Cochrane Headline outcomes only
Peto OR 0.83 [0.6, 1.15]
16 studies · 3299 participants
Moderate

Low molecular weight heparin vs vitamin K antagonist (VKA)

Major bleeding · patients with symptomatic VTE requiring long term treatment (3 months) for symptomatic VTE

LMWH may leads to lower incidence of major bleeding (treatment duration 3 months) compared with VKA (low certainty).

1 finding from 1 review

Vitamin K antagonists versus low‐molecular‐weight heparin for the long term treatment of symptomatic venous… 2017 · Cochrane Headline outcomes only
Peto OR 0.51 [0.32, 0.8]
16 studies · 3299 participants
Low

Low molecular weight heparin vs vitamin K antagonist (VKA)

Mortality (treatment duration 3 months) · patients with symptomatic VTE requiring long term treatment (3 months) for symptomatic VTE

LMWH showed no clear difference in mortality (treatment duration 3 months) compared with VKA (moderate certainty).

1 finding from 1 review

Vitamin K antagonists versus low‐molecular‐weight heparin for the long term treatment of symptomatic venous… 2017 · Cochrane Headline outcomes only
Peto OR 1.08 [0.75, 1.56]
16 studies · 3299 participants
Moderate

Intervention not reported

Cumulative incidence of any PTS (

The intervention showed no clear difference in cumulative incidence of any PTS ( (low certainty).

1 finding from 1 review

Compression therapy for prevention of post‐thrombotic syndrome 2017 · Cochrane Headline outcomes only
RR 0.62 [0.38, 1.01]
5 studies · 1393 participants
Low

Intervention not reported

Cumulative incidence of severe PTS (

The intervention showed no clear difference in cumulative incidence of severe PTS ( (low certainty).

1 finding from 1 review

Compression therapy for prevention of post‐thrombotic syndrome 2017 · Cochrane Headline outcomes only
RR 0.78 [0.53, 1.15]
4 studies · 1224 participants
Low

Intervention not reported

VTE: recurrence of DVT occurring in the first 2 weeks after initiation of treatment (

The intervention showed no clear difference in VTE: recurrence of DVT occurring in the first 2 weeks after… (low certainty).

1 finding from 1 review

Compression therapy for prevention of post‐thrombotic syndrome 2017 · Cochrane Headline outcomes only
RR 0.94 [0.69, 1.28]
4 studies · 1212 participants
Low

Intervention not reported

VTE: incidence of PE occurring in the first 2 weeks after initiation of treatment (

The intervention may leads to lower VTE: incidence of PE occurring in the first 2 weeks after initiation… (low certainty).

1 finding from 1 review

Compression therapy for prevention of post‐thrombotic syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1296 participants
Low

Intervention not reported

Adverse effects (

The intervention may leads to lower adverse effects ( (low certainty).

1 finding from 1 review

Compression therapy for prevention of post‐thrombotic syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1296 participants
Low

Intervention not reported

Patient satisfaction or QOL (

The intervention probably leads to lower patient satisfaction or QOL ( (moderate certainty).

1 finding from 1 review

Compression therapy for prevention of post‐thrombotic syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1377 participants
Moderate

Intervention not reported

Compliance (percentage compliance with treatment during 2‐year study periodl)

1 finding from 1 review

Compression therapy for prevention of post‐thrombotic syndrome 2017 · Cochrane Headline outcomes only
2
8 studies · 1639 participants
Low

Emergency endovascular aneurysm repair vs conventional open repair

Short‐term mortality (30‐day or in‐hospital) · people diagnosed with RAAA

Emergency endovascular aneurysm repair showed no clear difference in short‐term mortality (30‐day or in‐hospital) compared with conventional open repair (moderate certainty).

1 finding from 1 review

Endovascular treatment for ruptured abdominal aortic aneurysm 2017 · Cochrane Headline outcomes only
OR 0.88 [0.66, 1.16]
4 studies · 868 participants
Moderate

Emergency endovascular aneurysm repair vs conventional open repair

Endoleak (30‐day) · people diagnosed with RAAA

1 finding from 1 review

Endovascular treatment for ruptured abdominal aortic aneurysm 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 128 participants
Low

Emergency endovascular aneurysm repair vs conventional open repair

Myocardial infarction (0 to 30 days) · people diagnosed with RAAA

Emergency endovascular aneurysm repair showed no clear difference in complication: myocardial infarction (30‐day) compared with conventional open repair (low certainty).

1 finding from 1 review

Endovascular treatment for ruptured abdominal aortic aneurysm 2017 · Cochrane Headline outcomes only
OR 2.38 [0.34, 16.53]
2 studies · 139 participants
Low