Fungal Infection · prevention of sepsis and necrotizing enterocolitis in preterm infants
Lactoferrin supplementation may leads to lower fungal infection№ of participants: 3266(6 RCTs) compared with control (low certainty).
1 finding from 1 review
RR 0.23 [0.1, 0.54]
Studies not reported
Low
Chronic lung disease · prevention of sepsis and necrotizing enterocolitis in preterm infants
Lactoferrin supplementation showed no clear difference in chronic lung disease№ of participants: 2984(5 RCTs) compared with control (low certainty).
1 finding from 1 review
RR 1 [0.89, 1.12]
Studies not reported
Low
Length of hospital stay · prevention of sepsis and necrotizing enterocolitis in preterm infants
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Any late‐onset sepsis ‐ All infants [Data on only confirmed sepsis available] · prevention of sepsis and necrotizing enterocolitis in preterm infants
Lactoferrin supplementation with enteral feeds in combination with… may leads to lower any late‐onset sepsis ‐ All infants [Data on only confirmed sepsis… compared with placebo (low certainty).
1 finding from 1 review
NEC ≥ stage II · prevention of sepsis and necrotizing enterocolitis in preterm infants
It is very uncertain whether lactoferrin supplementation with enteral feeds in combination with… changes NEC ≥ stage II compared with placebo (very low certainty).
1 finding from 1 review
Length (cm) · the promotion of growth and prevention of infections in infants less than six months of age
1 finding from 1 review
Weight (g) after 6 months · the promotion of growth and prevention of infections in infants less than six months of age
1 finding from 1 review
Mean weight‐for‐age z‐score · the promotion of growth and prevention of infections in infants less than six months of age
1 finding from 1 review
Stunting · the promotion of growth and prevention of infections in infants less than six months of age
1 finding from 1 review
Weight‐for‐length/height z‐score at the end of the intervention Weight scale, measurement boards and child growth reference · the promotion of growth and prevention of infections in infants less than six months of age
1 finding from 1 review
Stunted after 6 months · the promotion of growth and prevention of infections in infants less than six months of age
Zinc supplementation showed no clear difference in stunted after 6 months compared with placebo; no treatment (moderate certainty).
1 finding from 1 review
Wasted after 6 months · the promotion of growth and prevention of infections in infants less than six months of age
Zinc supplementation showed no clear difference in wasted after 6 months compared with placebo; no treatment (low certainty).
1 finding from 1 review
Intervention not reported
PIPP score (difference between baseline and heel lance period) · Neonates
1 finding from 1 review
Intervention not reported
Duration of crying (seconds) during the first 3 minutes · Neonates
1 finding from 1 review
Intervention not reported
PIPP (maximum score within 3 minutes following lancing) · Neonates
1 finding from 1 review
Intervention not reported
PIPP score in first 45 seconds of eye examination · Neonates
1 finding from 1 review
Intervention not reported
PIPP score 5 minutes after eye examination · Neonates
1 finding from 1 review
Decline in bilirubin at 4 to 8 hours (μmol/L) · newborn infants with unconjugated hyperbilirubinaemia
1 finding from 1 review
Acute life‐threatening events · newborn infants with unconjugated hyperbilirubinaemia
1 finding from 1 review
Patient satisfaction · newborn infants with unconjugated hyperbilirubinaemia
1 finding from 1 review