Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,079 questions · 2,112 findings · 171 reviews · Eyes and Vision

No studies found 587 · 27.8%GRADE not reported 95 · 4.5%Very low 446 · 21.1%Low 557 · 26.4%Moderate 361 · 17.1%High 66 · 3.1%

Vitrectomy vs scleral buckling

Primary retinal reattachment at least 3 months after operation · people with simple rhegmatogenous retinal detachments

Pars plana vitrectomy (PPV) showed no clear difference in primary retinal reattachment at least 3 months after operation compared with scleral buckling (low certainty).

1 finding from 1 review

Vitrectomy vs scleral buckling

Final anatomical success at least 3 months after operation · people with simple rhegmatogenous retinal detachments

Pars plana vitrectomy (PPV) showed no clear difference in final anatomical success at least 3 months after operation compared with scleral buckling (low certainty).

1 finding from 1 review

Vitrectomy vs scleral buckling

Recurrence of retinal detachment at least 3 months after operation · people with simple rhegmatogenous retinal detachments

Pars plana vitrectomy (PPV) may leads to lower recurrence of retinal detachment at least 3 months after operation compared with scleral buckling (low certainty).

1 finding from 1 review

Vitrectomy vs scleral buckling

Quality of life (satisfaction with vision) at least 3 months after operation · people with simple rhegmatogenous retinal detachments

It is very uncertain whether pars plana vitrectomy (PPV) changes quality of life (satisfaction with vision) at least 3 months after… compared with scleral buckling (very low certainty).

1 finding from 1 review

Vitrectomy vs scleral buckling

Adverse effects (cataract development, choroidal detachment, new/iatrogenic breaks, postoperative proliferative vitreoretinopathy, postoperative increase in intraocular pressure, development of cystoid macular oedema, macular pucker, strabismus) a... · people with simple rhegmatogenous retinal detachments

Pars plana vitrectomy (PPV) may leads to higher adverse effects (cataract development, choroidal detachment,… compared with scleral buckling (low certainty).

1 finding from 1 review

Oral long‐chain omega‐3 PUFAs vs placebo or no treatment

Change in dry eye symptoms, measured using the OSDI score (ranging from 0 to 100 units, with a reduction in score indicating clinical improvement) at 1‐month (with actual · people with dry eyea

Oral long‐chain omega‐3 PUFAs (ie, EPA and DHA) showed no clear difference in change in dry eye symptoms, measured using the OSDI score (ranging… compared with placebo or no treatment (low certainty).

1 finding from 1 review