Findings

What do systematic reviews say?

1,139 questions · 1,173 findings · 89 reviews · Neuromuscular

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No studies found 302 · 25.7%GRADE not reported 119 · 10.1%Very low 267 · 22.8%Low 239 · 20.4%Moderate 177 · 15.1%High 69 · 5.9%

PIMOZIDE vs carbamazepine

Quality of life assessment 12 weeks after the start of treatment Not measured · patients with trigeminal neuralgia

1 finding from 1 review

Non‐antiepileptic drugs for trigeminal neuralgia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 96 participants
GRADE not reported

PIMOZIDE vs carbamazepine

Adverse effects The number of participants with adverse effects · patients with trigeminal neuralgia

1 finding from 1 review

Non‐antiepileptic drugs for trigeminal neuralgia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 96 participants
GRADE not reported

Tizanidine vs carbamazepine

Reduction in pain intensity · patients with trigeminal neuralgia

The review found no eligible studies for this question.

1 finding from 1 review

Non‐antiepileptic drugs for trigeminal neuralgia 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tizanidine vs carbamazepine

Quality of life assessment 12 weeks after the start of treatment Not measured · patients with trigeminal neuralgia

The review found no eligible studies for this question.

1 finding from 1 review

Non‐antiepileptic drugs for trigeminal neuralgia 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tizanidine vs carbamazepine

Adverse effects (not reported) · patients with trigeminal neuralgia

1 finding from 1 review

Non‐antiepileptic drugs for trigeminal neuralgia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 11 participants
GRADE not reported

Tocainide vs carbamazepine

Relief of pain · patients with trigeminal neuralgia

1 finding from 1 review

Non‐antiepileptic drugs for trigeminal neuralgia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
GRADE not reported

Tocainide vs carbamazepine

Reduction in pain intensity · patients with trigeminal neuralgia

The review found no eligible studies for this question.

1 finding from 1 review

Non‐antiepileptic drugs for trigeminal neuralgia 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tocainide vs carbamazepine

Quality of life assessment 12 weeks after the start of treatment Not measured · patients with trigeminal neuralgia

The review found no eligible studies for this question.

1 finding from 1 review

Non‐antiepileptic drugs for trigeminal neuralgia 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tocainide vs carbamazepine

Adverse effects · patients with trigeminal neuralgia

1 finding from 1 review

Non‐antiepileptic drugs for trigeminal neuralgia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
GRADE not reported

Proparacaine hydrochloride 0.5% eye drops vs placebo

Relief of pain · patients with trigeminal neuralgia

Proparacaine hydrochloride 0.5% eye drops showed no clear difference in immediate improvement in pain relief Number of participants improved… compared with placebo (low certainty).

1 finding from 1 review

Non‐antiepileptic drugs for trigeminal neuralgia 2013 · Cochrane Headline outcomes only
RR 1.06 [0.37, 2.99]
1 study · 47 participants
Low

Intervention not reported

Maximum voluntary contraction in dystrophinopathies % · patients with muscular dystrophies

1 finding from 1 review

Creatine for treating muscle disorders 2013 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 121 participants
High

Intervention not reported

Adverse events in glycogen storage disease type V · patients with metabolic myopathies

1 finding from 1 review

Creatine for treating muscle disorders 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 28 participants
GRADE not reported

Intervention not reported

Aggregate functional performance time (AFPT), intention‐to‐treat analysis % · patients with idiopathic inflammatory myopathies

1 finding from 1 review

Creatine for treating muscle disorders 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 37 participants
High

Intervention not reported

AFPT, valid compliant completer analysis % · patients with idiopathic inflammatory myopathies

1 finding from 1 review

Creatine for treating muscle disorders 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
High

Intervention not reported

Adverse events · patients with idiopathic inflammatory myopathies

1 finding from 1 review

Creatine for treating muscle disorders 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 37 participants
GRADE not reported

Intervention not reported

Maximum voluntary contraction in myotonic dystrophy type 1 % · patients with muscular dystrophies

1 finding from 1 review

Creatine for treating muscle disorders 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 76 participants
Moderate

Intervention not reported

Maximum voluntary contraction in myotonic dystrophy type 2 % · patients with muscular dystrophies

1 finding from 1 review

Creatine for treating muscle disorders 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 10 participants
High

Intervention not reported

Adverse events · patients with muscular dystrophies

1 finding from 1 review

Creatine for treating muscle disorders 2013 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 261 participants
High

Intervention not reported

Global assessment of improvement felt better · patients with muscular dystrophies

The intervention leads to higher global assessment of improvement felt better (high certainty).

1 finding from 1 review

Creatine for treating muscle disorders 2013 · Cochrane Headline outcomes only
RR 4.51 [2.33, 8.74]
4 studies · 183 participants
High

Intervention not reported

Maximum voluntary contraction in mitochondrial diseases % · patients with metabolic myopathies

1 finding from 1 review

Creatine for treating muscle disorders 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 38 participants
High