Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,501 questions · 1,558 findings · 115 reviews · Vascular

No studies found 346 · 22.2%GRADE not reported 90 · 5.8%Very low 281 · 18%Low 477 · 30.6%Moderate 313 · 20.1%High 51 · 3.3%

PTFE vs PTFE with vein cuff

Primary patency ( · people with peripheral vascular disease requiring below‐knee femoro‐popliteal bypass surgery

It is very uncertain whether PTFE changes primary patency (24 months) compared with PTFE with vein cuff (very low certainty).

2 findings from 1 review

PTFE vs PTFE with vein cuff

Secondary patency (24 months) · people with peripheral vascular disease requiring below‐knee femoro‐popliteal bypass surgery

It is very uncertain whether PTFE changes secondary patency (24 months) compared with PTFE with vein cuff (very low certainty).

1 finding from 1 review

PTFE vs PTFE with vein cuff

Limb salvage · people with peripheral vascular disease requiring below‐knee femoro‐popliteal bypass surgery

PTFE showed no clear difference in limb salvage (24 months) compared with PTFE with vein cuff (low certainty).

1 finding from 1 review

Autologous vein vs other graft types

Secondary patency (24 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery

Autologous vein may leads to lower secondary patency (60 months) compared with other graft types (low certainty).

1 finding from 1 review

PTFE vs Dacron

Primary patency ( · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery

PTFE showed no clear difference in primary patency (24 months) compared with dacron (low certainty).

2 findings from 1 review

PTFE vs Dacron

Secondary patency (24 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery

PTFE may leads to higher secondary patency (24 months) compared with dacron (low certainty).

1 finding from 1 review

PTFE vs Dacron

Limb salvage · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery

PTFE showed no clear difference in limb salvage (24 months) compared with dacron (low certainty).

1 finding from 1 review

Intervention not reported

Limb salvage at 30 days · patients seeking treatment for initial management of acute limb ischaemia

The intervention showed no clear difference in limb salvage at 30 days (low certainty).

1 finding from 1 review

Intervention not reported

Amputation at 30 days · patients seeking treatment for initial management of acute limb ischaemia

The intervention showed no clear difference in amputation at 30 days (low certainty).

1 finding from 1 review

Intervention not reported

Death at 30 days · patients seeking treatment for initial management of acute limb ischaemia

The intervention showed no clear difference in death at 30 days (moderate certainty).

1 finding from 1 review

Intervention not reported

Vessel patency at 30 days · patients seeking treatment for initial management of acute limb ischaemia

It is very uncertain whether the intervention changes vessel patency at 30 days (very low certainty).

1 finding from 1 review

Intervention not reported

Major haemorrhage at 30 days · patients seeking treatment for initial management of acute limb ischaemia

The intervention may leads to higher major haemorrhage at 30 days (low certainty).

1 finding from 1 review

Intervention not reported

Stroke at 30 days · patients seeking treatment for initial management of acute limb ischaemia

The intervention showed no clear difference in stroke at 30 days (low certainty).

1 finding from 1 review

Intervention not reported

Distal embolisation at 30 days · patients seeking treatment for initial management of acute limb ischaemia

It is very uncertain whether the intervention changes distal embolisation at 30 days (very low certainty).

1 finding from 1 review