Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

996 questions · 1,049 findings · 79 reviews · Dementia and Cognitive Improvement

No studies found 240 · 22.9%GRADE not reported 31 · 3%Very low 216 · 20.6%Low 253 · 24.1%Moderate 238 · 22.7%High 71 · 6.8%

procaine vs placebo

cognitive function improvement in "healthy" elderly persons Wechsler's memory scale2 · "healthy" old persons and demented women

procaine may leads to higher cognitive function improvement in "healthy" elderly persons… compared with placebo (low certainty).

1 finding from 1 review

procaine vs placebo

cognitive function improvement in demented women Wechsler's memory scale2 · "healthy" old persons and demented women

It is very uncertain whether procaine changes cognitive function improvement in demented women Wechsler's memory… compared with placebo (very low certainty).

1 finding from 1 review

procaine vs placebo

overall changes from baseline in "healthy persons7 ‐ not measured · "healthy" old persons and demented women

The review found no eligible studies for this question.

1 finding from 1 review

procaine vs placebo

overall changes from baseline in demented women · "healthy" old persons and demented women

It is very uncertain whether procaine changes overall changes from baseline in demented women compared with placebo (very low certainty).

1 finding from 1 review

procaine vs placebo

total adverse events in "healthy" persons · "healthy" old persons and demented women

procaine may leads to higher total adverse events in "healthy" persons compared with placebo (low certainty).

1 finding from 1 review