Cochrane · systematic review · CD003260

Cognitive training and cognitive rehabilitation for mild to moderate Alzheimer's disease and vascular dementia

Bahar‐Fuchs, A, Clare, L, Woods, B · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
13
current version
GRADE rated
8
No studies
5
Included studies
NR
No studies 5 · 38.5%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 23.1%Moderate 2 · 15.4%High 3 · 23.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Cognitive training compared to control in the short‐term (i.e. immediately post‐intervention) for early‐stage Alzheimer's disease and vascular dementia

Population: participants with early‐stage Alzheimer's disease and vascular dementia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Change in a global measure of cognition MMSE, ADAS‐Cog, Mattis Dementia Rating Scale
Cognitive training vs control
no estimate extracted6 studies · 173 participantsLow
Downgraded: risk of bias, imprecision
Change in participant's capacity for activities of daily living (Caregiver reported)
Cognitive training vs control
no estimate extracted4 studies · 107 participantsLow
Downgraded: imprecision, inconsistency
Change in participant's mood (self‐reported)
Cognitive training vs control
no estimate extracted4 studies · 114 participantsModerate
Downgraded: imprecision
Change in rates of admission to residential care-not measured
Cognitive training vs control
no estimate extractedNRNo studies
Change in measures of dementia severity-not measured
Cognitive training vs control
no estimate extractedNRNo studies
Change in immediate verbal memory scores
Cognitive training vs control
no estimate extracted7 studies · 201 participantsLow
Downgraded: risk of bias, imprecision
Change in self‐reported burden of care
Cognitive training vs control
no estimate extracted2 studies · 80 participantsModerate
Downgraded: imprecision

Cognitive rehabilitation compared to control in the short‐term (i.e. immediately post‐intervention) for early‐stage Alzheimer's disease and vascular dementia

Population: participants with early‐stage Alzheimer's disease and vascular dementia
6 questions
OutcomeEffectEvidenceStatus / GRADE
Change in a global measure of cognition-not measured
Cognitive rehabilitation vs control
no estimate extractedNRNo studies
Change in participant's self‐reported performance in relation to individual goals (COPM Performance, self‐reported) Canadian Occupational Performance Measure
Cognitive rehabilitation vs control
no estimate extracted1 study · 39 participantsHigh
Change in participant's mood (Depression, self‐reported) Hospital Anxiety and Depression Scale
Cognitive rehabilitation vs control
no estimate extracted1 study · 41 participantsHigh
Change in rates of admission to residential care-not measured
Cognitive rehabilitation vs control
no estimate extractedNRNo studies
Change in measures of dementia severity-not measured
Cognitive rehabilitation vs control
no estimate extractedNRNo studies
Change in self‐reported mood (Depression-caregiver)
Cognitive rehabilitation vs control
no estimate extracted1 study · 18 participantsHigh