Findings

What do systematic reviews say?

2,234 questions · 2,325 findings · 216 reviews · Airways

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No studies found 249 · 10.7%GRADE not reported 107 · 4.6%Very low 276 · 11.9%Low 751 · 32.3%Moderate 718 · 30.9%High 224 · 9.6%

Speech and language therapy vs healthy lifestyle advice

Objective cough counts (over 24‐hour period) · participants with chronic cough

1 finding from 1 review

Speech and language therapy for management of chronic cough 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 71 participants
Low

Speech and language therapy vs healthy lifestyle advice

Symptoms · participants with chronic cough

1 finding from 1 review

Speech and language therapy for management of chronic cough 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 87 participants
Low

Speech and language therapy vs healthy lifestyle advice

Clinical improvement (as defined by trialists) · participants with chronic cough

It is very uncertain whether speech and language therapy changes clinical improvement (as defined by trialists) compared with healthy lifestyle advice (very low certainty).

1 finding from 1 review

Speech and language therapy for management of chronic cough 2019 · Cochrane Headline outcomes only
OR 48.13 [13.53, 171.25]
1 study · 87 participants
Very low

Speech and language therapy vs healthy lifestyle advice

Cough · participants with chronic cough

Speech and language therapy showed no clear difference in subjective measures of cough (e.g. VAS/numerical cough scale score) compared with healthy lifestyle advice (low certainty).

1 finding from 1 review

Speech and language therapy for management of chronic cough 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 71 participants
Low

Speech and language therapy vs healthy lifestyle advice

Cough reflex sensitivity (as measured by cough challenge: capsaicin concentration required to provoke 5 coughs) · participants with chronic cough

1 finding from 1 review

Speech and language therapy for management of chronic cough 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 49 participants
Low

Speech and language therapy vs healthy lifestyle advice

Adverse events · participants with chronic cough

1 finding from 1 review

Speech and language therapy for management of chronic cough 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 75 participants
Low

Inhaled corticosteroids vs placebo

Lung function: FEV1 mL (change from baseline) · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 156 participants
Low

Inhaled corticosteroids vs placebo

Number of participants improved · people with bronchiectasis

Inhaled corticosteroids showed no clear difference in number of participants improved compared with placebo (low certainty).

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
OR 0.57 [0.24, 1.34]
1 study · 86 participants
Low

Inhaled corticosteroids vs placebo

Lung function (spirometry indices) ‐ FVC (in L, end study minus baseline values) · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 156 participants
Low

Inhaled corticosteroids vs placebo

Lung function (other indices) ‐ diffusion capacity % predicted (end of study) · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 57 participants
Low

Inhaled corticosteroids vs placebo

Lung function (other indices) ‐ RV % predicted (end of study values) · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 57 participants
Low

Inhaled corticosteroids vs placebo

Lung function (other indices) ‐ TLC % predicted (end of study values) · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 57 participants
Low

Inhaled corticosteroids vs placebo

Exacerbations · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 127 participants
Low

Inhaled corticosteroids vs placebo

Pseudomonas aeruginosa (P aeruginosa) colonisation · people with bronchiectasis

Inhaled corticosteroids showed no clear difference in pseudomonas aeruginosa (P aeruginosa) colonisation compared with placebo (low certainty).

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
OR 0.94 [0.45, 1.96]
2 studies · 156 participants
Low

Inhaled corticosteroids vs placebo

FEV1 % predicted: absolute change from baseline · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 86 participants
Low

Inhaled corticosteroids vs placebo

FVC (% predicted) Change from baseline · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 86 participants
Low

Influenza vaccine vs placebo

Total exacerbations per participant · COPD

1 finding from 1 review

Influenza vaccine for chronic obstructive pulmonary disease (COPD) 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 180 participants
Low

Influenza vaccine vs placebo

Early exacerbations per participant · COPD

1 finding from 1 review

Influenza vaccine for chronic obstructive pulmonary disease (COPD) 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 180 participants
Low

Influenza vaccine vs placebo

Late exacerbations per participant · COPD

1 finding from 1 review

Influenza vaccine for chronic obstructive pulmonary disease (COPD) 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 180 participants
Low

Influenza vaccine vs placebo

Days disability from respiratory illness · COPD

The review found no eligible studies for this question.

1 finding from 1 review

Influenza vaccine for chronic obstructive pulmonary disease (COPD) 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found