Findings

What do systematic reviews say?

962 questions · 1,000 findings · 69 reviews · Urology

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No studies found 196 · 19.6%GRADE not reported 33 · 3.3%Very low 198 · 19.8%Low 354 · 35.4%Moderate 206 · 20.6%High 13 · 1.3%

Lomefloxacin vs fluoroquinolones

Microbiological efficacy ‐ pathogen eradication · patients with chronic bacterial prostatitis

Lomefloxacin showed no clear difference in microbiological efficacy ‐ pathogen eradication at compared with comparator fluoroquinolone (low certainty).

1 finding from 1 review

Antimicrobial therapy for chronic bacterial prostatitis 2013 · Cochrane Headline outcomes only
RR 0.96 [0.8, 1.16]
2 studies · 116 participants
Low

Lomefloxacin vs fluoroquinolones

Clinical efficacy ‐ cure or improvement at · patients with chronic bacterial prostatitis

2 findings from 1 review

Antimicrobial therapy for chronic bacterial prostatitis 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported
Antimicrobial therapy for chronic bacterial prostatitis 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Lomefloxacin vs fluoroquinolones

Adverse effects of treatment ‐ any adverse effects · patients with chronic bacterial prostatitis

Lomefloxacin showed no clear difference in adverse effects of treatment ‐ any adverse effects compared with comparator fluoroquinolone (moderate certainty).

1 finding from 1 review

Antimicrobial therapy for chronic bacterial prostatitis 2013 · Cochrane Headline outcomes only
RR 0.64 [0.34, 1.21]
2 studies · 215 participants
Moderate

Ciprofloxacin vs fluoroquinolones

Microbiological efficacy ‐ pathogen eradication · patients with chronic bacterial prostatitis

It is very uncertain whether ciprofloxacin changes microbiological efficacy ‐ pathogen eradication at end of treatment compared with comparator fluoroquinolone (very low certainty).

1 finding from 1 review

Antimicrobial therapy for chronic bacterial prostatitis 2013 · Cochrane Headline outcomes only
RR 0.91 [0.7, 1.18]
3 studies · 851 participants
Very low

Antibiotics vs placebo

Bacteriuria · patients submitted to transrectal prostate biopsy

Antibiotic probably leads to lower bacteriuria compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 0.25 [0.15, 0.42]
8 studies · 870 participants
Moderate

Short course vs long course treatment

Hospitalization · patients submitted to transrectal prostate biopsy

Short course showed no clear difference in hospitalization compared with long course treatment (low certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 4.14 [0.47, 36.46]
2 studies · 366 participants
Low

Single‐dose vs multiple dose antibiotic

Bacteriuria · patients submitted to transrectal prostate biopsy

Single dose probably leads to higher bacteriuria compared with multiple dose antibiotic (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 1.98 [1.18, 3.33]
4 studies · 944 participants
Moderate

Single‐dose vs multiple dose antibiotic

Fever · patients submitted to transrectal prostate biopsy

Single dose showed no clear difference in fever compared with multiple dose antibiotic (low certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 2.84 [0.99, 8.16]
4 studies · 652 participants
Low

Single‐dose vs multiple dose antibiotic

UTI · patients submitted to transrectal prostate biopsy

Single dose showed no clear difference in UTI compared with multiple dose antibiotic (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 1.4 [0.73, 2.68]
5 studies · 1312 participants
Moderate

Single‐dose vs multiple dose antibiotic

Hospitalization · patients submitted to transrectal prostate biopsy

Single dose showed no clear difference in hospitalization compared with multiple dose antibiotic (low certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 3.1 [0.64, 15.06]
3 studies · 441 participants
Low

Oral vs systemic antibiotics

Bacteriuria · patients submitted to transrectal prostate biopsy

Oral showed no clear difference in bacteriuria compared with systemic antibiotic (IM or IV) (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 0.34 [0.06, 1.93]
3 studies · 354 participants
Moderate

Oral vs systemic antibiotics

Fever · patients submitted to transrectal prostate biopsy

Oral showed no clear difference in fever compared with systemic antibiotic (IM or IV) (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 1.8 [0.24, 13.45]
3 studies · 522 participants
Moderate

Oral vs systemic antibiotics

UTI · patients submitted to transrectal prostate biopsy

Oral showed no clear difference in UTI compared with systemic antibiotic (IM or IV) (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 0.85 [0.27, 2.7]
3 studies · 508 participants
Moderate

Oral vs systemic antibiotics

Hospitalization · patients submitted to transrectal prostate biopsy

Oral showed no clear difference in hospitalization compared with systemic antibiotic (IM or IV) (low certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 1.8 [0.24, 13.45]
2 studies · 407 participants
Low

Antibiotics vs placebo

Bacteremia · patients submitted to transrectal prostate biopsy

Antibiotic probably leads to lower bacteremia compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 0.67 [0.49, 0.92]
6 studies · 494 participants
Moderate

Antibiotics vs placebo

Fever · patients submitted to transrectal prostate biopsy

Antibiotic probably leads to lower fever compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 0.39 [0.23, 0.64]
9 studies · 820 participants
Moderate

Antibiotics vs placebo

UTI · patients submitted to transrectal prostate biopsy

Antibiotic probably leads to lower UTI compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 0.37 [0.22, 0.62]
5 studies · 1077 participants
Moderate

Antibiotics vs placebo

Hospitalization · patients submitted to transrectal prostate biopsy

Antibiotic probably leads to lower hospitalization compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 0.13 [0.03, 0.55]
3 studies · 650 participants
Moderate

Antibiotics vs placebo

Adverse event · patients submitted to transrectal prostate biopsy

Antibiotic showed no clear difference in adverse event compared with placebo (low certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 1.62 [0.23, 11.56]
2 studies · 127 participants
Low

Short course vs long course treatment

Bacteriuria · patients submitted to transrectal prostate biopsy

Short course probably leads to higher bacteriuria compared with long course treatment (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis for transrectal prostate biopsy 2011 · Cochrane Headline outcomes only
RR 2.09 [1.17, 3.73]
3 studies · 869 participants
Moderate