Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,252 questions · 2,353 findings · 210 reviews · Neonatal

No studies found 432 · 18.4%GRADE not reported 99 · 4.2%Very low 609 · 25.9%Low 737 · 31.3%Moderate 385 · 16.4%High 91 · 3.9%

High vs standard volume of unfortified human milk or term formula

Necrotising enterocolitis · preterm or low birth weight infants

It is very uncertain whether high changes necrotising enterocolitis compared with standard volume of unfortified human milk or term formula (very low certainty).

1 finding from 1 review

High vs standard volume of fortified human milk or preterm formula

Extrauterine growth restriction at discharge · preterm or low birth weight infants

High showed no clear difference in extrauterine growth restriction at discharge compared with standard volume of fortified human milk or preterm formula (low certainty).

1 finding from 1 review

High vs standard volume of fortified human milk or preterm formula

Necrotising enterocolitis · preterm or low birth weight infants

It is very uncertain whether high changes necrotising enterocolitis compared with standard volume of fortified human milk or preterm formula (very low certainty).

1 finding from 1 review

Tracheal suction vs no tracheal suction

Meconium aspiration syndrome (MAS) · non‐vigorous neonates born through meconium‐stained amniotic fluid

It is very uncertain whether tracheal suction changes meconium aspiration syndrome (MAS) compared with no tracheal suction (very low certainty).

1 finding from 1 review

Tracheal suction vs no tracheal suction

Moderate to severe hypoxic‐ischaemic encephalopathy (HIE) · non‐vigorous neonates born through meconium‐stained amniotic fluid

It is very uncertain whether tracheal suction changes moderate to severe hypoxic‐ischaemic encephalopathy (HIE) compared with no tracheal suction (very low certainty).

1 finding from 1 review

Tracheal suction vs no tracheal suction

Hypoxic ischaemic encephalopathy · non‐vigorous neonates born through meconium‐stained amniotic fluid

It is very uncertain whether tracheal suction changes any hypoxic‐ischaemic encephalopathy (HIE) compared with no tracheal suction (very low certainty).

1 finding from 1 review

Tracheal suction vs no tracheal suction

Need for mechanical ventilation · non‐vigorous neonates born through meconium‐stained amniotic fluid

It is very uncertain whether tracheal suction changes need for mechanical ventilation compared with no tracheal suction (very low certainty).

1 finding from 1 review