Adverse effects · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
1 finding from 1 review
Galeotti 2021: occasional skin irritation on the chin and three appliance breakages (one facemask, two Pushing Splints).
1 study · 42 participants
GRADE not reported
Overall success (composite of clinical and radiographic success) · Human permanent teeth with symptomatic irreversible pulpitis due to carious pulp exposure
Full pulpotomy showed a non-significant trend toward higher success than partial pulpotomy in mature teeth with irreversible pulpitis (ungraded).
1 finding from 1 review
OR 2.16 [0.92, 5.07]
3 studies
GRADE not reported
Midline deviation of the mandibular arch · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
One study found midline deviation more likely after unilateral than bilateral extraction (OR 11.6; single study; not GRADE-rated).
1 finding from 1 review
Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether topical curcumin gel changes burning sensation (VAS 0-100) compared with topical aloe vera gel (very low certainty).
1 finding from 1 review
defs index score · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age
It is very uncertain whether consumption of xylitol chewing gum by women (mothers) changes defs index score (categories) compared with consumption of CHX/xylitol gum by women, or CHX varnish applied to… (very low certainty).
2 findings from 1 review
Thorild 2003 defs score categories (very low-certainty): 1-3 defs RR 0.48 (95% CI 0.15 to 1.54); 3-4 defs RR 0.85 (95% CI 0.18 to 3.98); >=5 defs RR 0.28 (95% CI 0.01 to 6.78); 96 participants.
1 study · 96 participants
Very low
MD -0.28 [-0.83, 0.27]
1 study · 96 participants
Very low
Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask (RME) or modified facemask showed no clear difference in wits appraisal compared with surgically-anchored appliance (miniscrews or miniplates); GRADE not reported.
1 finding from 1 review
Overjet · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask with rapid maxillary expansion (RME) showed no clear difference in overjet compared with pushing Splints; GRADE not reported.
1 finding from 1 review
Adverse effects · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
In partial pulpotomy, MTA had significantly higher success than calcium hydroxide (OR 2.81; ungraded).
Show 2 more findings
Change in bleeding on probing (BOP) · Adults (> 18 years) with recurrent periodontitis, receiving supportive (maintenance) periodontal care
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after… showed no clear difference in change in bleeding on probing (BOP) compared with subgingival instrumentation (SI) alone (hand or power-driven, or…; GRADE not reported.
2 findings from 1 review
Intolerance to spicy food (participant-reported proxy) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
Antioxidants (lycopene, curcumin, Oxitard) led to lower intolerance to spicy food (participant-reported proxy) compared with placebo or no active treatment; GRADE not reported.
1 finding from 1 review
Gingival index (GI) · Children and/or adolescents (<18 years) without background systemic disease
Probiotics probably make little to no difference to the gingival index versus control (MD 0.04, 95%CI -0.18 to 0.27; low certainty).
1 finding from 1 review
Bacterial growth inhibition · Streptococcus mutans (in vitro cultures and biofilms)
No meta-analysis was conducted; five included studies reported inhibition of Streptococcus mutans growth with grape seed extract or fractions.
1 finding from 1 review
no estimate extracted
5 studies
GRADE not reported
Muscle pain when chewing · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes muscle pain when chewing compared with no treatment or placebo (non-occlusal or transparent-foil placebo… (very low certainty).
1 finding from 1 review
Pain at 72 hours · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or systemic involvement)
It is very uncertain whether postoperative systemic antibiotics… changes pain at 72 hours compared with matched placebo, partial or total chemo-mechanical debridement and… (very low certainty).
1 finding from 1 review
Self-esteem (Oral Aesthetic Subjective Impact Score, OASIS) · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask led to lower self-esteem (Oral Aesthetic Subjective Impact Score, OASIS) compared with untreated control (no treatment); GRADE not reported.
3 findings from 1 review
MD -4.00 [-7.40, -0.60]
1 study · 69 participants
GRADE not reported
MD -2.20 [-7.31, 2.91]
1 study · 65 participants
GRADE not reported
MD -3.40 [-7.99, 1.19]
1 study · 63 participants
GRADE not reported
Association between patient age and number of ICLs · Patients (permanent dentition) during or after fixed orthodontic treatment with fixed (multibracket) appliances
Patient age was not significantly associated with the number of ICLs (ungraded).
1 finding from 1 review
Dental caries · Primary school children in Ethiopia
Absence of toothpaste use was not significantly associated with dental caries (OR 1.42, 95% CI -1.278 to 4.109, p=0.3029; ungraded).
1 finding from 1 review
OR 1.42 [-1.278, 4.109]
Studies not reported
GRADE not reported
Change in bleeding on probing (BOP) · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
It is very uncertain whether adjunctive antimicrobial photodynamic therapy (aPDT) applied after… changes change in bleeding on probing (BOP) compared with subgingival instrumentation (SI) alone (hand or power-driven, or… (very low certainty).
2 findings from 1 review
Reduction in previous year's academic score · Primary school children in Ethiopia
Dental caries was associated with higher odds of a reduction in the previous year's academic score (OR 5.51, 95% CI 1.952-9.066; ungraded).
1 finding from 1 review
OR 5.51 [1.952, 9.066]
Studies not reported
GRADE not reported