Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,060 questions · 1,105 findings · 84 reviews · Metabolic and Endocrine Disorders

No studies found 434 · 39.3%GRADE not reported 32 · 2.9%Very low 246 · 22.3%Low 237 · 21.4%Moderate 132 · 11.9%High 24 · 2.2%

Intervention not reported

Severe hypoglycaemic episodes (number of severe hypoglycaemic episodes)

The intervention may leads to higher severe hypoglycaemic episodes (number of severe hypoglycaemic… (low certainty).

1 finding from 1 review

Intervention not reported

Infectious complications (infectious complication after surgery (e.g. pneumonia, urinary tract infection))

The intervention showed no clear difference in infectious complications (infectious complication after surgery… (low certainty).

1 finding from 1 review

Intervention not reported

Cardiovascular events (incidents that may cause damage to the cardiovascular system)

The intervention may leads to lower cardiovascular events (incidents that may cause damage to the… (low certainty).

1 finding from 1 review

Intervention not reported

Renal failure (number of individuals with an elevation of serum creatinine greater than 2 mg/dL or requiring dialysis)

The intervention showed no clear difference in renal failure (number of individuals with an elevation of serum… (low certainty).

1 finding from 1 review

Parathyroidectomy vs observation

Hospitalisation for hypercalcaemia, renal impairment or pancreatitis · people with primary hyperparathyroidism

Parathyroidectomy showed no clear difference in hospitalisation for hypercalcaemia, renal impairment or pancreatitis compared with observation (low certainty).

1 finding from 1 review