Self-esteem (Piers-Harris self-concept scale) · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask showed no clear difference in self-esteem (Piers-Harris self-concept scale) compared with untreated control (no treatment); GRADE not reported.
3 findings from 1 review
MD 0.60 [-2.57, 3.77]
1 study · 63 participants
GRADE not reported
MD 1.50 [-0.96, 3.96]
1 study · 69 participants
GRADE not reported
MD -0.30 [-4.17, 3.57]
1 study · 65 participants
GRADE not reported
Intervention not reported
Overall success (composite of clinical and radiographic success)
1 finding from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether buccal fat pad graft changes maximal mouth opening (interincisal distance) compared with extended nasolabial flap (very low certainty).
3 findings from 1 review
MD 6.50 [-10.72, 23.72]
1 study · 8 participants
Very low
MD -7.25 [-14.19, -0.31]
1 study · 8 participants
Very low
MD 6.00 [-11.36, 23.36]
1 study · 8 participants
Very low
ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Facemask with rapid maxillary expansion (RME) showed no clear difference in ANB compared with facemask with alternating rapid maxillary expansion and constriction… (low certainty).
1 finding from 1 review
Streptococcus mutans count · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35)
The antibacterial (S. mutans) effect of TiO2 nanoparticles was conflicting across two RCTs (ungraded).
1 finding from 1 review
Severity of joint noise · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Intervention not reported
Overall success (composite of clinical and radiographic success)
1 finding from 1 review
First-time bracket failure · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
Resin-modified glass ionomer cement showed no difference in first-time bracket failure, with certainty not graded.
1 finding from 1 review
No differences were observed in the proportions of patients experiencing first-time bracket failures when participants were bonded with either resin adhesive or RM-GIC (p > 0.05).
1 study · 197 participants
GRADE not reported
Caries arrest · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
Spontaneous space closure is much more likely in the maxilla than the mandible (OR 7.77; low certainty).
1 finding from 1 review
Change in gingival recession (REC) · Adults (> 18 years) with peri-implant mucositis, receiving active treatment
The review found no eligible studies for this question.
1 finding from 1 review
Probing pocket depth · Adults in case-control studies (oral cancer patients vs healthy controls)
Periodontal pocket depth did not differ significantly between oral cancer patients and controls (SMD 1.64, 95% CI -0.20 to 3.47; very high heterogeneity); ungraded.
1 finding from 1 review
Intervention not reported
Overall success (composite of clinical and radiographic success)
1 finding from 1 review
Intervention not reported
Spontaneous space closure
The intervention led to higher spontaneous space closure; GRADE not reported.
1 finding from 1 review
OR 42.0
1 study
GRADE not reported
Dental caries · Children (<18 years) with vs without dental caries
ApaI(rs7975232) recessive model: CC vs CA+AA was not significantly associated with dental caries (OR 0.87); ungraded.
1 finding from 1 review
Determinants of oral diseases · Adult residents of slums and non-slum urban settings of LMICs
Older age, lower education and income, poor oral hygiene, and disadvantaged residential setting were associated with oral diseases; directions varied across studies.
1 finding from 1 review
no estimate extracted
14 studies
GRADE not reported
Wits appraisal · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)
Chin cup (600 g force) showed no clear difference in wits appraisal compared with chin cup (300 g force); GRADE not reported.
1 finding from 1 review
Self-reported joint pain when chewing · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes self-reported joint pain when chewing compared with pharmacological therapy (very low certainty).
1 finding from 1 review
Early childhood caries (ECC) · Preschool children (<6 years)
After excluding Peres et al. (2017), breastfeeding for less than 24 months was associated with fewer caries (RR 0.49, 95% CI 0.39 to 0.62; I²=6%).
2 findings from 1 review
Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether pentoxifylline changes burning sensation (VAS 0-100) compared with spirulina (very low certainty).
1 finding from 1 review