Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,079 questions · 2,112 findings · 171 reviews · Eyes and Vision

No studies found 587 · 27.8%GRADE not reported 95 · 4.5%Very low 446 · 21.1%Low 557 · 26.4%Moderate 361 · 17.1%High 66 · 3.1%

Topical mydriatics vs intracameral mydriatics

AE: posterior capsule rupture · patients undergoing cataract surgery

Topical mydriatics showed no clear difference in AE: posterior capsule rupture compared with intracameral mydriatics (low certainty).

2 findings from 1 review

Photobiomodulation treatment vs no treatment/sham

Adverse events: AMD progression at 12 months Defined as increased drusen volume or onset of advanced AMD. Conversion to exudative AMD at 12 months Assessed by clinical examination and retinal optical coherence tomography. · people with non‐exudative AMD (AREDS 2 to 4)

Photobiomodulation treatment showed no clear difference in adverse events: AMD progression at 12 months Defined as increased… compared with sham or no treatment (low certainty).

1 finding from 1 review

Surgery vs no surgery

Proportion of eyes with gain in VA by 0.3 logMAR or greater · people with epiretinal membrane

It is very uncertain whether surgery changes proportion of eyes with gain in VA by 0.3 logMAR or greater compared with no surgery (very low certainty).

1 finding from 1 review

Surgery vs no surgery

Proportion of eyes with loss in VA by 0.3 logMAR or greater · people with epiretinal membrane

Surgery may leads to lower proportion of eyes with loss in VA by 0.3 logMAR or greater compared with no surgery (low certainty).

1 finding from 1 review