Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

715 questions · 767 findings · 53 reviews · Back and Neck

No studies found 149 · 19.4%GRADE not reported 41 · 5.3%Very low 168 · 21.9%Low 226 · 29.5%Moderate 156 · 20.3%High 27 · 3.5%

Spinal manipulative therapy plus another intervention vs the intervention alone

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with chronic LBP
3 findings from 1 review

Spinal manipulative therapy vs inert interventions

Recovery at one month · adults with chronic low‐back pain

It is very uncertain whether spinal manipulative therapy changes recovery at 1 month compared with inert interventions (very low certainty).

2 findings from 1 review

Spinal manipulative therapy vs sham SMT

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with chronic LBP
3 findings from 1 review

Intervention not reported

Pain intensity various scales long‐term · adults with chronic low‐back pain
1 finding from 1 review

Intervention not reported

Functional status (generic) Sickness Impact Profile (0‐136) short‐term · adults with chronic low‐back pain
1 finding from 1 review

Intervention not reported

Functional status (generic) Sickness Impact Profile (0‐136) intermediate‐term · adults with chronic low‐back pain
1 finding from 1 review

Intervention not reported

Functional status (generic) Sickness Impact Profile (0‐136) long‐term · adults with chronic low‐back pain
1 finding from 1 review

Intervention not reported

Depression Beck Depression Inventory (0‐63) short‐term · adults with chronic low‐back pain
1 finding from 1 review

Intervention not reported

Depression Beck Depression Inventory (0‐63) intermediate‐term · adults with chronic low‐back pain
1 finding from 1 review

Intervention not reported

Depression Beck Depression Inventory (0‐63) long‐term · adults with chronic low‐back pain
1 finding from 1 review

Intervention not reported

Functional status (generic) various scales short‐term · adults with chronic low‐back pain
1 finding from 1 review