Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

671 questions · 731 findings · 61 reviews · Drugs and Alcohol

No studies found 57 · 7.8%GRADE not reported 39 · 5.3%Very low 186 · 25.4%Low 239 · 32.7%Moderate 171 · 23.4%High 39 · 5.3%

Anticonvulsant vs placebo

Leaving the study early · patients with alcohol dependence

Anticonvulsants showed no clear difference in dropouts compared with placebo (moderate certainty).

1 finding from 1 review

Anticonvulsant vs placebo

Continuous abstinence rate at · patients with alcohol dependence

Anticonvulsants showed no clear difference in continuous abstinence compared with placebo (moderate certainty).

1 finding from 1 review

Anticonvulsant vs placebo

Adverse events ‐ Withdrawn for medical reasons · patients with alcohol dependence

Anticonvulsants showed no clear difference in adverse events—withdrawn for medical reasons compared with placebo (moderate certainty).

1 finding from 1 review