Cochrane · systematic review · CD007210

Maintenance treatments for opiate ‐dependent adolescents

Minozzi, S, Amato, L, Bellisario, C, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

Drugs and AlcoholAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 100%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Buprenorphine maintenance compared to buprenorphine detoxification for opiate‐dependent adolescents

4 questions
OutcomeEffectEvidenceStatus / GRADE
Drop‐outs Number of participants who did not complete the study
Buprenorphine maintenance vs buprenorphine detoxification
RR 0.37 [0.26, 0.54]1 study · 152 participantsLow
Downgraded: risk of bias, imprecision
Use of primary substance Patients with positive urine test at the end of treatment
Buprenorphine maintenance vs buprenorphine detoxification
RR 0.97 [0.78, 1.22]1 study · 152 participantsLow
Downgraded: risk of bias, imprecision
Self reported use at 12‐month
Buprenorphine maintenance vs buprenorphine detoxification
RR 0.73 [0.57, 0.95]1 study · 152 participantsLow
Downgraded: risk of bias, imprecision
Enrolment in addiction treatment at 12‐month
Buprenorphine maintenance vs buprenorphine detoxification
RR 1.33 [0.94, 1.88]1 study · 152 participantsLow
Downgraded: risk of bias, imprecision