Adverse events · Patients with pain after surgical removal of lower wisdom teeth (third molars) requiring bone removal or with baseline moderate to severe…
1 finding from 1 review
The majority of adverse events were minor in nature and usually included nausea, vomiting, headaches and dizziness. Side effect profiles have not been included in a meta-analysis as multiple adverse events were…
7 studies
GRADE not reported
Post-operative infection · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
2 mm locking titanium plates showed no clear difference in post-operative infection compared with 2 mm non-locking titanium plates; GRADE not reported.
1 finding from 1 review
OR 0.90 [0.1, 7]
1 study
GRADE not reported
Average pain scores (0-100 VAS) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
Singh 2012 evaluated VAS pain at weeks 1, 4, 8 and month 3 and reported no significant difference between the groups, without supporting details.
1 study
GRADE not reported
Time to eruption of the permanent canine · Children with palatally displaced maxillary canines (at least 80% aged 10 to 13 years); trials with craniofacial syndromes or anomalies…
1 finding from 1 review
Maximum voluntary jaw opening (mm), change from baseline · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) showed no clear difference in maximum voluntary jaw opening (mm), change from baseline compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review
Complications (adverse effects) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Intra-articular injection of sodium hyaluronate showed no clear difference in complications (adverse effects) compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.
1 finding from 1 review
Patient satisfaction and pain experience during extraction of the primary canine · Children with palatally displaced maxillary canines (at least 80% aged 10 to 13 years); trials with craniofacial syndromes or anomalies…
The review found no eligible studies for this question.
1 finding from 1 review
Presence of TMJ sounds · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Intra-articular injection of sodium hyaluronate led to lower presence of TMJ sounds compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.
1 finding from 1 review
Extraoral masticatory muscle tenderness (number of tender sites), change from baseline · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) showed no clear difference in extraoral masticatory muscle tenderness (number of tender sites),… compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review
Laser therapy
Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
The review found no eligible studies for this question.
1 finding from 1 review
Complications (adverse effects) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Diclofenac sodium (oral NSAID) showed no clear difference in complications (adverse effects) compared with occlusal splint therapy; GRADE not reported.
1 finding from 1 review
Reported pain (mm on VAS), change from baseline · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) showed no clear difference in reported pain (mm on VAS), change from baseline compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) showed no clear difference in brief Pain Inventory (BPI) - pain intensity, change from baseline compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review
Prevalence of eruption/non-eruption of the palatally displaced permanent canine (successful eruption) · Children with palatally displaced maxillary canines (at least 80% aged 10 to 13 years); trials with craniofacial syndromes or anomalies…
1 finding from 1 review
Narrative (not pooled, not GRADE-rated). Leonardi 2004: successful eruption 80% with extraction plus cervical pull headgear, significantly higher than the untreated control group (Chi2 14.9; P<0.01). Baccetti 2008: the…
2 studies · 81 participants
GRADE not reported
Incidence or prevalence of root resorption of the impacted canine and/or incisors and cyst formation · Children with palatally displaced maxillary canines (at least 80% aged 10 to 13 years); trials with craniofacial syndromes or anomalies…
The review found no eligible studies for this question.
1 finding from 1 review
Improvement in the vertical position or angulation of the ectopic canine, measured from radiographs · Children with palatally displaced maxillary canines (at least 80% aged 10 to 13 years); trials with craniofacial syndromes or anomalies…
1 finding from 1 review
Changes in the position of the displaced canine measured from radiographs, reported by both trials as medians (non-normal distribution): changes in the inclination of the canine to the midline, the distance of the…
2 studies
GRADE not reported
Pain on palpation of the affected/contralateral TMJ and masticatory muscles · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Intra-articular injection of sodium hyaluronate led to lower pain on palpation of the affected/contralateral TMJ and masticatory… compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.
1 finding from 1 review
Pain on palpation of the affected and contralateral TMJ and masticatory muscles presented similar frequencies regardless of the time (Analyses 1.4-1.12); no statistically significant differences reported. Point…
1 study · 40 participants
GRADE not reported
Extent of mandibular movement (maximum jaw opening, lateral and contralateral movement, jaw protrusion) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Intra-articular injection of sodium hyaluronate showed no clear difference in extent of mandibular movement (maximum jaw opening, lateral and… compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.
1 finding from 1 review
None of the mean differences between interventions for the measures of jaw movements (maximum jaw opening, lateral movement to affected side, contralateral movement, jaw protrusion; Analyses 1.16-1.27) showed…
1 study · 40 participants
GRADE not reported
Reassurance / behavioral management (control of contributory factors)
Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
The review found no eligible studies for this question.
1 finding from 1 review
Pain-free maximum jaw opening (mm), change from baseline · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) showed no clear difference in pain-free maximum jaw opening (mm), change from baseline compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review