Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Paracetamol (single administration, any dose) vs placebo

Maternal drug adverse effects (sleepiness) · women with perineal pain following childbirth

Paracetamol (single administration, any dose) showed no clear difference in maternal drug adverse effects (sleepiness) compared with placebo (low certainty).

1 finding from 1 review

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

B2: Maternal sepsis – an all women · women undergoing caesarean section

It is very uncertain whether antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) changes maternal sepsis compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (very low certainty).

1 finding from 1 review

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

Endometritis · women undergoing caesarean section

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) showed no clear difference in maternal endometritis compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (low certainty).

1 finding from 1 review

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

Wound infection · women undergoing caesarean section

It is very uncertain whether antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) changes maternal wound infection compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (very low certainty).

1 finding from 1 review

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

Maternal urinary tract infection · women undergoing caesarean section

It is very uncertain whether antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) changes maternal urinary tract infection compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (very low certainty).

1 finding from 1 review

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

Maternal composite adverse effects · women undergoing caesarean section

It is very uncertain whether antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) changes maternal composite adverse effects compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (very low certainty).

1 finding from 1 review

Probiotics vs placebo

Diagnosis of gestational diabetes · preventing gestational diabetes

Probiotics showed no clear difference in diagnosis of gestational diabetes mellitus compared with placebo (low certainty).

1 finding from 1 review

Probiotics vs placebo

Mortality or morbidity composite · preventing gestational diabetes

Probiotics showed no clear difference in mortality or morbidity composite compared with placebo (low certainty).

1 finding from 1 review

Probiotics vs placebo

Hypoglycaemia · preventing gestational diabetes

Probiotics showed no clear difference in hypoglycaemia as defined by trialists compared with placebo (low certainty).

1 finding from 1 review