Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

592 questions · 793 findings · 32 reviews · Periodontology

No studies found 148 · 18.7%GRADE not reported 429 · 54.1%Very low 137 · 17.3%Low 53 · 6.7%Moderate 14 · 1.8%High 12 · 1.5%

Powered toothbrush, ultrasonic action vs Multidimensional powered toothbrush

Gingivitis (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)
1 finding from 1 review

Multidimensional powered toothbrush vs Side to side action powered toothbrush

Plaque (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)
1 finding from 1 review
  • Different powered toothbrushes for plaque control and gingival health 2010 · Cochrane All outcomes
    Short term (1-3 months)
    Analysis 5.1 Plaque < 3 months (Turesky): 3 trials, 236 participants (Goyal 2005; Patters 2005; Zimmer 2005); significant heterogeneity (P < 0.1; I2 = 96%), so no statistical pooling was undertaken.
    3 studies · 236 participants
    GRADE not reported

Powered toothbrush, counter oscillation action vs Circular powered toothbrush

Gingivitis (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)
1 finding from 1 review
  • Different powered toothbrushes for plaque control and gingival health 2010 · Cochrane All outcomes
    Short term (1-3 months) · Adolescents
    Trimpeneers 1997 reported a significant difference in favour of the counter oscillation brush for gingival index at 2 months over a circular mode of action brush; data were unsuitable for meta-analysis.
    1 study · 36 participants
    GRADE not reported

Powered toothbrush, side-to-side action vs Counter oscillation powered toothbrush

Gingivitis (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)

Side to side action powered toothbrush showed no clear difference in gingivitis (level reduction) compared with counter oscillation powered toothbrush; GRADE not reported.

1 finding from 1 review

Multidimensional powered toothbrush vs Side to side action powered toothbrush

Staining · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)
1 finding from 1 review

Powered toothbrush, rotation oscillation action vs Circular powered toothbrush

Plaque (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)

Rotation oscillation powered toothbrush showed no clear difference in plaque (level reduction) compared with circular powered toothbrush; GRADE not reported.

1 finding from 1 review

Powered toothbrush, side-to-side action vs Circular powered toothbrush

Gingivitis (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)

Side to side action powered toothbrush led to higher gingivitis (level reduction) compared with circular powered toothbrush; GRADE not reported.

1 finding from 1 review

Powered toothbrush, rotation oscillation action vs Circular powered toothbrush

Gingivitis (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)

Rotation oscillation powered toothbrush led to higher gingivitis (level reduction) compared with circular powered toothbrush; GRADE not reported.

1 finding from 1 review

Powered toothbrush, side-to-side action vs Circular powered toothbrush

Plaque (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)
1 finding from 1 review
  • Different powered toothbrushes for plaque control and gingival health 2010 · Cochrane All outcomes
    Short term (1-3 months)
    Analysis 3.1 Plaque < 3 months (Turesky): 1 trial (Yankell 1997), 64 participants; totals not selected; no significant difference between side to side and circular for plaque in the short term.
    1 study · 64 participants
    GRADE not reported

Enamel matrix derivative (EMD; Emdogain) vs placebo or control

Aesthetics · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

Enamel matrix derivative (EMD; Emdogain) showed no clear difference in aesthetics compared with placebo or control (same surgical or non-surgical intervention… (low certainty).

1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs Various bone grafting (BG) procedures (animal-derived or synthetic bone / bioactive ceramic filler)

Aesthetics · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

The review found no eligible studies for this question.

1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs placebo or control

Change in gingival recession (REC) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

Enamel matrix derivative (EMD; Emdogain) showed no clear difference in change in gingival recession (REC) compared with placebo or control (same surgical or non-surgical intervention… (low certainty).

1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs placebo or control

Marginal bone level change · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs Various bone grafting (BG) procedures (animal-derived or synthetic bone / bioactive ceramic filler)

Change in probing attachment level (PAL) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs Guided tissue regeneration (GTR) with barriers

Change in probing pocket depth (PPD) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

Enamel matrix derivative (EMD; Emdogain) showed no clear difference in change in probing pocket depth (PPD) compared with guided tissue regeneration (GTR) with barriers (low certainty).

1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs Guided tissue regeneration (GTR) with barriers

Change in gingival recession (REC) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

Enamel matrix derivative (EMD; Emdogain) may leads to higher change in gingival recession (REC) compared with guided tissue regeneration (GTR) with barriers (low certainty).

1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs placebo or control

Change in probing pocket depth (PPD) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

Enamel matrix derivative (EMD; Emdogain) may leads to higher change in probing pocket depth (PPD) compared with placebo or control (same surgical or non-surgical intervention… (low certainty).

1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs placebo or control

Change in probing attachment level (PAL) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

Enamel matrix derivative (EMD; Emdogain) may leads to higher change in probing attachment level (PAL) compared with placebo or control (same surgical or non-surgical intervention… (low certainty).

1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs Guided tissue regeneration (GTR) with barriers

Tooth loss · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review