Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

671 questions · 731 findings · 61 reviews · Drugs and Alcohol

No studies found 57 · 7.8%GRADE not reported 39 · 5.3%Very low 186 · 25.4%Low 239 · 32.7%Moderate 171 · 23.4%High 39 · 5.3%

Intervention not reported

Alcohol‐related problems: 4+ months—web/computer normative feedback · university or college students

The intervention showed no clear difference in alcohol‐related problems: 4+ months—web/computer normative feedback (low certainty).

1 finding from 1 review

Intervention not reported

Alcohol‐related problems: 4+ months—individual face‐to‐face normative feedback · university or college students

The intervention showed no clear difference in alcohol‐related problems: 4+ months—individual face‐to‐face… (moderate certainty).

1 finding from 1 review

Intervention not reported

Binge drinking: 4+ months (all delivery modes) · university or college students

The intervention showed no clear difference in binge drinking: 4+ months (all delivery modes) (moderate certainty).

1 finding from 1 review

Intervention not reported

Quantity of drinking: 4+ months (all delivery modes) · university or college students

The intervention showed no clear difference in quantity of drinking: 4+ months (all delivery modes) (moderate certainty).

1 finding from 1 review

Intervention not reported

Frequency: 4+ months—web/computer normative feedback · university or college students

The intervention showed no clear difference in frequency: 4+ months—web/computer normative feedback (moderate certainty).

1 finding from 1 review

Intervention not reported

Frequency: 4+ months—individual face‐to‐face normative feedback · university or college students

The intervention showed no clear difference in frequency: 4+ months—individual face‐to‐face normative feedback (moderate certainty).

1 finding from 1 review

Intervention not reported

Frequency: 4+ months—group face‐to‐face normative feedback · university or college students

The intervention showed no clear difference in frequency: 4+ months—group face‐to‐face normative feedback (low certainty).

1 finding from 1 review

Intervention not reported

Peak BAC: 4+ months (all delivery modes) · university or college students

The intervention showed no clear difference in peak BAC: 4+ months (all delivery modes) (low certainty).

1 finding from 1 review

Intervention not reported

Typical BAC: 4+ months—individual face‐to‐face normative feedback · university or college students

The intervention showed no clear difference in typical BAC: 4+ months—individual face‐to‐face normative feedback (moderate certainty).

1 finding from 1 review

Anticonvulsant vs placebo

Dropout · patients with cocaine dependence

Any anticonvulsant showed no clear difference in dropout Number of participants who did not complete the treatment compared with placebo (moderate certainty).

1 finding from 1 review

Anticonvulsant vs placebo

Number of participants using cocaine during the treatment (as days/week by urine tests or self report) Number of participants that reported the use of cocaine during the treatment · patients with cocaine dependence

Any anticonvulsant showed no clear difference in use of cocaine (self reported or objective) Number of participants… compared with placebo (moderate certainty).

1 finding from 1 review

Anticonvulsant vs placebo

Participants with at least some Side Effects · patients with cocaine dependence

Any anticonvulsant may leads to higher side effect Number of participants reporting at least 1 side effect… compared with placebo (low certainty).

1 finding from 1 review