Non‐serious adverse events · children with non‐paracetamol (acetaminophen)‐related acute liver failure
N‐acetylcysteine showed no clear difference in non‐serious adverse events compared with placebo (low certainty).
1 finding from 1 review
Quality of life ‐ not reported · children with non‐paracetamol (acetaminophen)‐related acute liver failure
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse events · adult patients with non‐paracetamol (acetaminophen)‐related acute liver failure
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Liver Transplant · adult patients with non‐paracetamol (acetaminophen)‐related acute liver failure
N‐acetylcysteine showed no clear difference in liver transplant compared with placebo (low certainty).
1 finding from 1 review
Resolution of encephalopathy and coagulopathy · adult patients with non‐paracetamol (acetaminophen)‐related acute liver failure
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Non‐serious adverse events · adult patients with non‐paracetamol (acetaminophen)‐related acute liver failure
N‐acetylcysteine showed no clear difference in non‐serious adverse events compared with placebo (low certainty).
1 finding from 1 review
Quality of life · adult patients with non‐paracetamol (acetaminophen)‐related acute liver failure
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · children with non‐paracetamol (acetaminophen)‐related acute liver failure
N‐acetylcysteine showed no clear difference in all‐cause mortality compared with placebo (low certainty).
1 finding from 1 review
Serious adverse events · children with non‐paracetamol (acetaminophen)‐related acute liver failure
N‐acetylcysteine showed no clear difference in serious adverse events compared with placebo (low certainty).
1 finding from 1 review
Liver Transplant · children with non‐paracetamol (acetaminophen)‐related acute liver failure
N‐acetylcysteine showed no clear difference in liver Transplant compared with placebo (low certainty).
1 finding from 1 review
Intervention not reported
Interventions · people with liver cirrhosis and ascites
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Aldosterone antagonists plus loop diuretics plus albumin (No direct RCT) · people with liver cirrhosis and ascites
It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics plus albumin (No direct… (very low certainty).
1 finding from 1 review
HR 1.06 [0.57, 2.16]
Studies not reported
Very low
Intervention not reported
Aldosterone antagonists plus loop diuretics plus peritoneovenous shunt (No direct RCT) · people with liver cirrhosis and ascites
It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics plus peritoneovenous… (very low certainty).
1 finding from 1 review
HR 0.97 [0.4, 2.43]
Studies not reported
Very low
Intervention not reported
Aldosterone antagonists plus loop diuretics plus systemic vasoconstrictors (No direct RCT) · people with liver cirrhosis and ascites
It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics plus systemic… (very low certainty).
1 finding from 1 review
HR 0.42 [0.15, 1.22]
Studies not reported
Very low
Intervention not reported
Aldosterone antagonists (No direct RCT) · people with liver cirrhosis and ascites
It is very uncertain whether the intervention changes aldosterone antagonists (No direct RCT) (very low certainty).
1 finding from 1 review
HR 1.92 [0.24, 20.64]
Studies not reported
Very low
Intervention not reported
Aldosterone antagonists plus loop diuretics plus systemic vasoconstrictors plus paracentesis plus fluid replacement (No direct RCT) · people with liver cirrhosis and ascites
It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics plus systemic… (very low certainty).
1 finding from 1 review
HR 1.11 [0.02, 39.77]
Studies not reported
Very low
Intervention not reported
Aldosterone antagonists plus loop diuretics plus systemic vasoconstrictors plus systemic vasodilator (No direct RCT) · people with liver cirrhosis and ascites
It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics plus systemic… (very low certainty).
1 finding from 1 review
HR 0.61 [0.02, 9.17]
Studies not reported
Very low
Intervention not reported
Aldosterone antagonists plus loop diuretics plus systemic vasodilator (No direct RCT) · people with liver cirrhosis and ascites
It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics plus systemic… (very low certainty).
1 finding from 1 review
HR 0.62 [0.03, 9.1]
Studies not reported
Very low
Intervention not reported
Systemic vasoconstrictors plus albumin (No direct RCT) · people with liver cirrhosis and ascites
It is very uncertain whether the intervention changes systemic vasoconstrictors plus albumin (No direct RCT) (very low certainty).
1 finding from 1 review
HR 2.62 [0.41, 19.28]
Studies not reported
Very low
Intervention not reported
Serious adverse events (number of people) · people with liver cirrhosis and ascites
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found