Findings

What do systematic reviews say?

4,860 questions · 64,864 findings · 4,913 reviews · Headline outcomes only

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No studies found 13,869 · 21.4%GRADE not reported 3,491 · 5.4%Very low 16,300 · 25.1%Low 17,338 · 26.7%Moderate 10,900 · 16.8%High 2,966 · 4.6%

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Extracorporeal shockwave therapy vs sham

Outcomes ( · men with Peyronie's disease (palpable plaque or pain)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Potassium paraaminobenzoate vs placebo

Degree of penile curvature · men with acute (maximum of 12 months) Peyronie's disease with no prior treatment and no evidence of calcified plaques (pain during…

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Extracorporeal shockwave therapy vs sham

Patient‐reported ability to have intercourse · men with Peyronie's disease (palpable plaque or pain)

It is very uncertain whether extracorporeal shock wave treatment (ESWT) changes patient‐reported ability to have intercourse compared with sham (very low certainty).

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
RR 1.6 [0.71, 3.6]
1 study · 26 participants
Very low

Extracorporeal shockwave therapy vs sham

Quality of life · men with Peyronie's disease (palpable plaque or pain)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 130 participants
Low

Extracorporeal shockwave therapy vs sham

Treatment‐related adverse effects · men with Peyronie's disease (palpable plaque or pain)

It is very uncertain whether extracorporeal shock wave treatment (ESWT) changes treatment‐related adverse effects compared with sham (very low certainty).

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
RR 2.73 [0.74, 10.14]
3 studies · 166 participants
Very low

Extracorporeal shockwave therapy vs sham

Degree of penile curvature · men with Peyronie's disease (palpable plaque or pain)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 166 participants
Low

Extracorporeal shockwave therapy vs sham

Treatment discontinuation · men with Peyronie's disease (palpable plaque or pain)

It is very uncertain whether extracorporeal shock wave treatment (ESWT) changes discontinuation from treatment compared with sham (very low certainty).

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
RR 0.57 [0.06, 5.65]
4 studies · 238 participants
Very low

Penile traction therapy vs no treatment (short‐term)

Outcomes ( · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Penile traction therapy vs no treatment (short‐term)

Patient‐reported ability to have intercourse · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Penile traction therapy vs no treatment (short‐term)

Quality of life · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 82 participants
Very low

Penile traction therapy vs no treatment (short‐term)

Treatment‐related adverse effects · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 90 participants
Very low

Penile traction therapy vs no treatment (short‐term)

Degree of penile curvature · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 89 participants
Very low

Potassium paraaminobenzoate vs placebo

Treatment discontinuation · men with acute (maximum of 12 months) Peyronie's disease with no prior treatment and no evidence of calcified plaques (pain during…

It is very uncertain whether potassium paraaminobenzoate changes discontinuation from treatment compared with placebo (very low certainty).

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
RR 1.36 [0.72, 2.58]
1 study · 103 participants
Very low

Penile traction therapy vs no treatment (short‐term)

Treatment discontinuation · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

It is very uncertain whether penile traction therapy changes discontinuation from treatment compared with no treatment (short‐term) (very low certainty).

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
RR 0.86 [0.31, 2.36]
2 studies · 182 participants
Very low

Injectional interferon alpha‐2B vs Normal saline

Outcomes ( · men with chronic (≥ 12 months) Peyronie's disease (single plaque)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Injectional interferon alpha‐2B vs Normal saline

Patient‐reported ability to have intercourse · men with chronic (≥ 12 months) Peyronie's disease (single plaque)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Injectional interferon alpha‐2B vs Normal saline

Quality of life · men with chronic (≥ 12 months) Peyronie's disease (single plaque)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Platelet‐rich growth factor + hyaluronic acid vs platelet‐rich growth factor

Ulcer healing · pressure ulcer

It is very uncertain whether platelet‐rich growth factor + hyaluronic acid changes complete ulcer healing compared with platelet‐rich growth factor (very low certainty).

1 finding from 1 review

Dressings and topical agents containing hyaluronic acid for chronic wound healing 2023 · Cochrane Headline outcomes only
RR 1.17 [0.58, 2.35]
1 study · 65 participants
Very low

Lysine hyaluronate vs sodium hyaluronate

Health‐related quality of life ‐ not reported · people with pressure ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Dressings and topical agents containing hyaluronic acid for chronic wound healing 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lysine hyaluronate vs sodium hyaluronate

Pain · people with pressure ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Dressings and topical agents containing hyaluronic acid for chronic wound healing 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found