Question · asked by 1 review

Potassium paraaminobenzoate vs placebo: Treatment discontinuation

It is very uncertain whether potassium paraaminobenzoate changes discontinuation from treatment compared with placebo (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Potassium paraaminobenzoate vs placebo
Discontinuation from treatment · men with acute (maximum of 12 months) Peyronie's disease with no prior treatment and no evidence of calcified plaques…
It is very uncertain whether potassium paraaminobenzoate changes discontinuation from treatment compared with placebo (very low certainty).
Non‐surgical therapies for Peyronie's disease (2023) · Cochrane Headline outcomes only
RR 1.36 [0.72, 2.58]1 study · 103 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Non‐surgical therapies for Peyronie's disease
2023 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.