Participants with serious adverse events · people who have been exposed to SARS‐CoV‐2
1 finding from 1 review
Negative PCR for SARS‐CoV‐2 on respiratory samples at day 14 from enrolmentd · adults with mild to severe COVID‐19
Hydroxychloroquine (HCQ) showed no clear difference in negative PCR for SARS‐CoV‐2 on respiratory samples at day 14 from… compared with standard care or placebo (low certainty).
1 finding from 1 review
Progression to mechanical ventilation · adults with mild to severe COVID‐19
Hydroxychloroquine (HCQ) showed no clear difference in progression to mechanical ventilation compared with standard care or placebo (moderate certainty).
1 finding from 1 review
Time to clinical improvement · adults with mild to severe COVID‐19
It is very uncertain whether hydroxychloroquine (HCQ) changes time to clinical improvement compared with standard care or placebo (very low certainty).
1 finding from 1 review
Participants with any adverse events · adults with mild to severe COVID‐19
Hydroxychloroquine (HCQ) probably leads to higher participants with any adverse events compared with standard care or placebo (moderate certainty).
1 finding from 1 review
Participants with serious adverse events · adults with mild to severe COVID‐19
Hydroxychloroquine (HCQ) showed no clear difference in participants with serious adverse events compared with standard care or placebo (low certainty).
1 finding from 1 review
Participants with prolongation of QT‐interval on ECG · adults with mild to severe COVID‐19
It is very uncertain whether hydroxychloroquine (HCQ) changes participants with prolongation of QT‐interval on ECG compared with standard care or placebo (very low certainty).
1 finding from 1 review
Development of confirmed COVID‐19 at 14 days from enrolment · people who have been exposed to SARS‐CoV‐2
It is very uncertain whether hydroxychloroquine (HCQ) changes development of confirmed COVID‐19 at 14 days from enrolment compared with placebo (very low certainty).
1 finding from 1 review
Hospitalized due to COVID‐19c · people who have been exposed to SARS‐CoV‐2
It is very uncertain whether hydroxychloroquine (HCQ) changes hospitalized due to COVID‐19c compared with placebo (very low certainty).
1 finding from 1 review
Intervention not reported
Index test · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for index tests: any 1…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Specificities 99% and 100% · children evaluated in inpatient or outpatient settings Index tests: Xpert MTB/RIF Role: an initial test Threshold for index tests: an…
1 finding from 1 review
Intervention not reported
≥ 1 of cough, fever, or poor weight gain · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for index tests: any 1…
1 finding from 1 review
Intervention not reported
≥ 1 of cough, fever, or decreased playfulness · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for index tests: any 1…
1 finding from 1 review
Intervention not reported
≥ 1 of cough, fever, poor weight gain, or tuberculosis close contact (WHO 4‐symptom symptom screen) · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for index tests: any 1…
1 finding from 1 review
Intervention not reported
Estimation (95% Cl) · children with close tuberculosis contacts Index test: abnormal chest radiography Role: an initial test Threshold for index tests: author…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Pooled sensitivity 87% (75% to 93%) · children with close tuberculosis contacts Index test: abnormal chest radiography Role: an initial test Threshold for index tests: author…
1 finding from 1 review
Intervention not reported
Pooled specificity 99% (68% to 100%) · children with close tuberculosis contacts Index test: abnormal chest radiography Role: an initial test Threshold for index tests: author…
1 finding from 1 review
Intervention not reported
Estimations · children evaluated in inpatient or outpatient settings Index tests: Xpert MTB/RIF Role: an initial test Threshold for index tests: an…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Sensitivities 43% and 100% · children evaluated in inpatient or outpatient settings Index tests: Xpert MTB/RIF Role: an initial test Threshold for index tests: an…
1 finding from 1 review
Intervention not reported
Index test, population · people living with HIV and non‐hospitalized people in high‐risk groups
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found