Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,079 questions · 2,112 findings · 171 reviews · Eyes and Vision

No studies found 587 · 27.8%GRADE not reported 95 · 4.5%Very low 446 · 21.1%Low 557 · 26.4%Moderate 361 · 17.1%High 66 · 3.1%

Rituximab vs placebo

CAS improvement (decrease) by 2 or more points · thyroid‐associated ophthalmopathy

It is very uncertain whether summary of findings table ‐ Rituximab changes CAS improvement (decrease) by 2 or more points compared with placebo (very low certainty).

1 finding from 1 review

Rituximab vs placebo

NOSPECS improvement (decrease) by 2 classes or more · thyroid‐associated ophthalmopathy

It is very uncertain whether summary of findings table ‐ Rituximab changes NOSPECS improvement (decrease) by 2 classes or more compared with placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Failure of re‐epithelialisation by day 21 post‐injury Image analysis of digital photographs · people with moderate acute ocular burns

It is very uncertain whether the intervention changes failure of re‐epithelialisation by day 21 post‐injury Image analysis… (very low certainty).

1 finding from 1 review

Intervention not reported

Symblepharon Presence of symblepharon · people with severe acute ocular burns

The intervention showed no clear difference in symblepharon Presence of symblepharon (low certainty).

1 finding from 1 review

Intervention not reported

Corneal neovascularisation Number of quadrants affected · people with moderate acute ocular burns

It is very uncertain whether the intervention changes corneal neovascularisation Number of quadrants affected (very low certainty).

1 finding from 1 review

Intervention not reported

Symblepharon Presence of symblepharon · people with moderate acute ocular burns

It is very uncertain whether the intervention changes symblepharon Presence of symblepharon (very low certainty).

1 finding from 1 review

Intervention not reported

Failure of re‐epithelialisation by day 21 post‐injury Image analysis of digital photographs · people with severe acute ocular burns

The intervention showed no clear difference in failure of re‐epithelialisation by day 21 post‐injury Image analysis… (low certainty).

1 finding from 1 review

Intervention not reported

Corneal neovascularisation Number of quadrants or central cornea involved · people with severe acute ocular burns

The intervention showed no clear difference in corneal neovascularisation Number of quadrants or central cornea… (low certainty).

1 finding from 1 review

Binocular iPad treatment vs occlusion therapy

Visual acuity · 5‐ to 8‐year‐old children with amblyopia
2 findings from 1 review

Binocular iPad treatment vs occlusion therapy

Change in the interocular difference in contrast sensitivity Any validated test, from baseline to 16 (± 2) weeks · 5‐ to 8‐year‐old children with amblyopia

The review found no eligible studies for this question.

1 finding from 1 review

Binocular iPad treatment vs occlusion therapy

Measurable change in stereopsis after 8 (± 2) weeks and 16 (± 2) weeks of intervention 'Real change' in stereopsis is defined as a change in stereoacuity of two or more octaves. · 5‐ to 8‐year‐old children with amblyopia

The review found no eligible studies for this question.

1 finding from 1 review