Specificity for dental caries diagnosis · Children and adults with primary or permanent dentition
Specificity ranged from 83% to 100% across 13 studies; no meta-analysis or GRADE rating was reported.
1 finding from 1 review
no estimate extracted
13 studies
GRADE not reported
Enamel demineralization (DIAGNOdent score) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
TiO2-modified composite favored lower DIAGNOdent scores, with certainty not graded.
1 finding from 1 review
Change in bleeding on probing (BOP) · Adults (> 18 years) with peri-implant mucositis, receiving active treatment
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after… led to higher change in bleeding on probing (BOP) compared with submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT; GRADE not reported.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
Over-dominant model (CC+TT vs CT) at FokI(rs10735810) showed no significant association with caries (OR 0.83); ungraded.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
FokI(rs2228570) allelic model: A vs G was not significantly associated with dental caries (OR 1.07); ungraded.
1 finding from 1 review
Primary caries prevention · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Difficulty in swallowing (participant-reported proxy) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
Oxitard (antioxidant) led to lower difficulty in swallowing (participant-reported proxy) compared with aloe vera gel; GRADE not reported.
1 finding from 1 review
Participant satisfaction or quality of life · People with temporomandibular disorders (TMD)
Occlusal splint showed no clear difference in participant satisfaction or quality of life compared with behavioural therapy (counselling, CBT, relaxation, self-care…; GRADE not reported.
1 finding from 1 review
Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years
Fluoride varnish applied before 4 years of age may leads to higher fluorosis (percentage prevalence in permanent teeth) compared with no fluoride varnish application (low certainty).
1 finding from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
Pentoxifylline may leads to lower maximal mouth opening (interincisal distance) compared with spirulina (low certainty).
1 finding from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether hydrocortisone plus hyaluronidase (intralesional) changes maximal mouth opening (interincisal distance) compared with placebo or no active treatment (very low certainty).
1 finding from 1 review
Muscle pain at rest · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes muscle pain at rest compared with no treatment or placebo (non-occlusal or transparent-foil placebo… (very low certainty).
1 finding from 1 review
Range of mandibular motion · People with temporomandibular disorders (TMD)
Occlusal splint showed no clear difference in range of mandibular motion compared with physical therapy (ultrasound, exercise, sensorimotor training,…; GRADE not reported.
1 finding from 1 review
Root resorption · People receiving orthodontic treatment with fixed appliances (upper and/or lower full arch)
The review found no eligible studies for this question.
1 finding from 1 review
Muscle pain at rest · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Enamel acid resistance (cross-sectional microhardness) · Human enamel in pits and fissures (in situ / ex vivo)
Nd:YAG laser increased enamel acid resistance versus untreated enamel in pits and fissures (ungraded, 1 ex-vivo study, no pooled estimate).
1 finding from 1 review
Dental caries in children · Children aged 4 to 6 years whose mothers' prenatal vitamin D status was assessed
Among children aged 4-6 years, prenatal vitamin D deficiency is associated with significantly higher odds of dental caries (OR 1.44, 95% CI 1.32-1.56); ungraded.
1 finding from 1 review
Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic review and… 2024 All outcomesPrenatal exposure; dental caries at 4 to 6 years · Observational pregnancy/birth-cohort studies (one cross-sectional), mostly in developed countries (USA, Canada, Japan, Australia, Spain, Netherlands, Poland, New Zealand, Turkey) · Children's age subgroup: 4 to 6 years
OR 1.44 [1.32, 1.56]
8 studies
GRADE not reported
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether intralesional triamcinolone changes maximal mouth opening (interincisal distance) compared with intralesional salvianolic acid B (very low certainty).
1 finding from 1 review
Antioxidant capacity · Streptococcus mutans (in vitro cultures and biofilms)
No meta-analysis was conducted; one included study reported antioxidant properties of cranberry fractions.
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Dental pain or sensitivity · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review