Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,860 questions · 64,864 findings · 4,913 reviews · Headline outcomes only

No studies found 13,869 · 21.4%GRADE not reported 3,491 · 5.4%Very low 16,300 · 25.1%Low 17,338 · 26.7%Moderate 10,900 · 16.8%High 2,966 · 4.6%

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Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention

Change in visual loss associated with PSR: visual loss is defined by the deterioration of visual acuity of 3 lines or more with the Snellen chart · type 1 or type 2 diabetics

It is very uncertain whether blood pressure intervention/intensive blood pressure intervention changes visual acuity (loss of 3 lines or more) by 5 years compared with placebo/standard blood pressure intervention (very low certainty).

1 finding from 1 review

Blood pressure intervention/intensive blood pressure intervention vs placebo/standard blood pressure intervention

Adverse events: hypotension · type 1 or type 2 diabetics

Blood pressure intervention/intensive blood pressure intervention may leads to higher adverse events—hypotension compared with placebo/standard blood pressure intervention (low certainty).

1 finding from 1 review

Hand hygiene vs control

Composite of acute respiratory illness, influenza‐like illness, laboratory‐confirmed influenza · general population and healthcare workers

Hand hygiene may leads to lower composite of acute respiratory illness, influenza‐like illness,… compared with control (low certainty).

1 finding from 1 review

Medical/surgical masks vs no masks

Viral respiratory illness ‐ laboratory‐confirmed influenza/SARS‐CoV‐2 · general population

Medical/surgical masks showed no clear difference in viral respiratory illness ‐ laboratory‐confirmed influenza/SARS‐CoV‐2 compared with no masks (moderate certainty).

1 finding from 1 review