Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,444 questions · 1,518 findings · 135 reviews · Infectious Diseases

No studies found 135 · 8.9%GRADE not reported 150 · 9.9%Very low 350 · 23.1%Low 420 · 27.7%Moderate 321 · 21.1%High 142 · 9.4%

MDA vs no MDA

Confirmed malaria illness incidence · People of all ages living in an area with very low to low endemicity of P vivax malaria (< 10% prevalence)

It is very uncertain whether MDA changes confirmed malaria illness incidence compared with no MDA (very low certainty).

1 finding from 1 review

MDA vs no MDA

Parasitaemia incidence · People of all ages living in an area with moderate to high endemicity of P falciparum malaria (≥ 10% prevalence)

MDA probably leads to lower parasitaemia incidence compared with no MDA (moderate certainty).

1 finding from 1 review

MDA vs no MDA

Confirmed malaria illness incidence · People of all ages living in an area with moderate to high endemicity of P falciparum malaria (≥ 10% prevalence)

MDA showed no clear difference in confirmed malaria illness incidence compared with no MDA (low certainty).

1 finding from 1 review

MDA vs no MDA

Parasitaemia incidence · People of all ages living in an area with very low to low endemicity of P falciparum malaria ( < 10% prevalence)

MDA probably leads to lower parasitaemia incidence compared with no MDA (moderate certainty).

1 finding from 1 review

MDA vs no MDA

Confirmed malaria illness incidence · People of all ages living in an area with very low to low endemicity of P falciparum malaria ( < 10% prevalence)

It is very uncertain whether MDA changes confirmed malaria illness incidence compared with no MDA (very low certainty).

2 findings from 1 review

Intervention not reported

Clinical malaria · children under 12 months of age

The intervention probably leads to lower clinical malaria (moderate certainty).

1 finding from 1 review

Intervention not reported

Hospital admission for any reason · malaria in infants

The intervention showed no clear difference in hospital admission for any reason (moderate certainty).

1 finding from 1 review

Intervention not reported

Parasitaemia · malaria in infants

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Anaemia · malaria in infants

The intervention showed no clear difference in anaemia (moderate certainty).

1 finding from 1 review

Intervention not reported

Clinical malaria · malaria in infants

The intervention probably leads to lower clinical malaria (moderate certainty).

1 finding from 1 review