Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,293 questions · 2,395 findings · 172 reviews · Gut

No studies found 420 · 17.5%GRADE not reported 60 · 2.5%Very low 821 · 34.3%Low 602 · 25.1%Moderate 397 · 16.6%High 95 · 4%

Fecal microbiota transplantation vs control

Any adverse events with use of FMT for maintenance of remission in UC (RR > 1 favors the control) · Patients with quiescent ulcerative colitis

It is very uncertain whether fecal microbiota transplantation changes any adverse events with use of FMT for maintenance of remission in… compared with control (very low certainty).

1 finding from 1 review

Fecal microbiota transplantation vs control

Maintenance of endoscopic remission in UC (RR > 1 favors FMT) · Patients with quiescent ulcerative colitis

It is very uncertain whether fecal microbiota transplantation changes maintenance of endoscopic remission in UC (RR > 1 favors FMT) compared with control (very low certainty).

1 finding from 1 review

Synbiotic vs placebo

Severity of pain (at study end, using the Faces Pain Scale) · children (4 to 18 years) with functional abdominal pain disorders

It is very uncertain whether synbiotic changes severity of pain (at study end, using the Faces Pain Scale) compared with placebo (very low certainty).

1 finding from 1 review

Probiotics vs placebo

Severity of pain (at study end, using the Faces Pain Scale) · children (4 to 18 years) with functional abdominal pain disorders

It is very uncertain whether probiotic changes severity of pain (at study end, using the Faces Pain Scale) compared with placebo (very low certainty).

1 finding from 1 review

Erythromycin plus nasogastric tube lavage vs no intervention/placebo plus nasogastric tube lavage

All‐cause mortality · people with acute UGIH

It is very uncertain whether erythromycin plus nasogastric tube lavage changes all‐cause mortality compared with no intervention/placebo plus nasogastric tube lavage (very low certainty).

1 finding from 1 review