Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,510 questions · 2,653 findings · 194 reviews · Gynaecology and Fertility

No studies found 531 · 20%GRADE not reported 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Embryo culture with low oxygen concentration vs embryo culture with atmospheric oxygen concentration

Clinical pregnancy rate · Patients with clinical pregnancy rate

Embryo culture with low oxygen concentration probably leads to higher clinical pregnancy rate compared with embryo culture with atmospheric oxygen concentration (moderate certainty).

1 finding from 1 review

Embryo culture with low oxygen concentration vs embryo culture with atmospheric oxygen concentration

Multiple pregnancy rate · Patients with multiple pregnancy rate

Embryo culture with low oxygen concentration showed no clear difference in multiple‐pregnancy rate compared with embryo culture with atmospheric oxygen concentration (low certainty).

1 finding from 1 review

Embryo culture with low oxygen concentration vs embryo culture with atmospheric oxygen concentration

Miscarriage · patients with miscarriage rate

Embryo culture with low oxygen concentration showed no clear difference in miscarriage rate compared with embryo culture with atmospheric oxygen concentration (low certainty).

1 finding from 1 review

Embryo culture with low oxygen concentration vs embryo culture with atmospheric oxygen concentration

Congenital abnormalities · patients with congenital abnormalities

It is very uncertain whether embryo culture with low oxygen concentration changes congenital abnormalities compared with embryo culture with atmospheric oxygen concentration (very low certainty).

1 finding from 1 review

rFSH vs urinary‐derived gonadotrophins

Ongoing pregnancy / live birth rate per woman · patients with ovarian stimulation in assisted reproductive technology cycles

rFSH showed no clear difference in live birth (or ongoing pregnancy) by urinary gonadotrophin compared with urinary gonadotrophins: primary analyses (high certainty).

4 findings from 1 review
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rFSH vs urinary‐derived gonadotrophins

OHSS by urinary gonadotrophin · patients with ovarian stimulation in assisted reproductive technology cycles

rFSH showed no clear difference in OHSS by urinary gonadotrophin compared with urinary gonadotrophins: primary analyses (high certainty).

1 finding from 1 review