Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,293 questions · 2,395 findings · 172 reviews · Gut

No studies found 420 · 17.5%GRADE not reported 60 · 2.5%Very low 821 · 34.3%Low 602 · 25.1%Moderate 397 · 16.6%High 95 · 4%

Manual acupuncture vs cisapride

Adverse effects Discomfort after treatment · patients with functional dyspepsia

It is very uncertain whether manual acupuncture changes adverse effects Discomfort after treatment compared with cisapride (very low certainty).

1 finding from 1 review

Manual acupuncture vs cisapride

Frequency of FD symptoms Number of FD attacks per week · patients with functional dyspepsia

It is very uncertain whether manual acupuncture changes frequency of FD symptoms Number of FD attacks per week compared with cisapride (very low certainty).

1 finding from 1 review

Manual acupuncture vs domperidone

Symptom scores of FD Graded by 4 levels1 · patients with functional dyspepsia

Manual acupuncture showed no clear difference in symptom scores of FD Graded by 4 levels1 compared with domperidone (low certainty).

1 finding from 1 review

Manual‐electroacupuncture vs domperidone

Symptom scores of FD Graded by 4 levels1 · patients with functional dyspepsia

It is very uncertain whether manual‐electroacupuncture changes symptom scores of FD Graded by 4 levels1 compared with domperidone (very low certainty).

1 finding from 1 review

Manual‐electroacupuncture vs domperidone

Symptom scores of ulceration subtype Graded by 4 levels1 · patients with functional dyspepsia

It is very uncertain whether manual‐electroacupuncture changes symptom scores of ulceration subtype Graded by 4 levels1 compared with domperidone (very low certainty).

1 finding from 1 review

Manual‐electroacupuncture vs domperidone

Regurgitation · patients with functional dyspepsia

It is very uncertain whether manual‐electroacupuncture changes symptom scores of regurgitation subtype Graded by 4 levels1 compared with domperidone (very low certainty).

1 finding from 1 review

Manual‐electroacupuncture vs domperidone

Symptom scores of dyskinesia subtype Graded by 4 levels1 · patients with functional dyspepsia

It is very uncertain whether manual‐electroacupuncture changes symptom scores of dyskinesia subtype Graded by 4 levels1 compared with domperidone (very low certainty).

1 finding from 1 review

Manual‐electroacupuncture vs domperidone

Symptom scores of nonspecific subtype Graded by 4 levels1 · patients with functional dyspepsia

It is very uncertain whether manual‐electroacupuncture changes symptom scores of nonspecific subtype Graded by 4 levels1 compared with domperidone (very low certainty).

1 finding from 1 review

Antioxidants vs control intervention

Pain free by end of study (day 6) · patients with chronic pancreatitis and pancreatic pain

Antioxidant showed no clear difference in pain‐free participants compared with control intervention (low certainty).

1 finding from 1 review

Antioxidants vs control intervention

Adverse effects—parallel trials · patients with chronic pancreatitis and pancreatic pain

Antioxidant probably leads to higher adverse effects—parallel trials compared with control intervention (moderate certainty).

1 finding from 1 review

Antioxidants vs control intervention

Adverse effects—cross‐over trials (unpaired data) · patients with chronic pancreatitis and pancreatic pain

Antioxidant probably leads to higher adverse effects—cross‐over trials (unpaired data) compared with control intervention (moderate certainty).

1 finding from 1 review

Proton pump inhibitors (PPI) vs control

Number of participants with worsening scores in corporal atrophy · people with pre‐malignant lesions

Proton pump inhibitor showed no clear difference in number of participants with worsening scores in corporal atrophy compared with control (low certainty).

1 finding from 1 review