Cochrane · systematic review · CD008945
Antioxidants for pain in chronic pancreatitis
Ahmed Ali, U, Jens, S, Busch, ORC, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 25%Moderate 3 · 75%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Antioxidant versus control intervention for pain in chronic pancreatitis
Population: patients with pain in chronic pancreatitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain visual analogue score Scale from 0 to 10 Antioxidant vs control intervention | no estimate extracted | 4 studies · 129 participants | Moderate Downgraded: risk of bias |
Pain‐free participants Antioxidant vs control intervention | RR 1.73 [0.95, 3.15] | 3 studies · 264 participants | Low Downgraded: risk of bias, inconsistency |
Adverse effects—parallel trials Antioxidant vs control intervention | RR 4.43 [1.6, 12.29] | 3 studies · 212 participants | Moderate Downgraded: risk of bias |
Adverse effects—cross‐over trials (unpaired data) Antioxidant vs control intervention | RR 5.8 [1.56, 21.53] | 5 studies · 192 participants | Moderate Downgraded: risk of bias |