Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,510 questions · 2,653 findings · 194 reviews · Gynaecology and Fertility

No studies found 531 · 20%GRADE not reported 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Long protocol continued GnRH agonist vs long protocol stop GnRH agonist

Clinical pregnancies Number of clinical pregnancies per woman randomised · women undergoing pituitary suppression in assisted reproduction

Long protocol continued GnRH agonist showed no clear difference in clinical pregnancies Number of clinical pregnancies per woman… compared with long protocol stop GnRH agonist (low certainty).

1 finding from 1 review

Long protocol vs long protocol (extend GnRHa 12 days after HCG)

Live birth or ongoing pregnancy · women undergoing pituitary suppression in assisted reproduction

Long protocol (GnRHa until HCG) showed no clear difference in live birth and ongoing pregnancies per woman randomised compared with long protocol (extend GnRHa 12 days after HCG) (low certainty).

1 finding from 1 review

Long protocol vs long protocol (extend GnRHa 12 days after HCG)

Clinical pregnancy rate · women undergoing pituitary suppression in assisted reproduction

Long protocol (GnRHa until HCG) showed no clear difference in clinical pregnancies per woman randomised compared with long protocol (extend GnRHa 12 days after HCG) (low certainty).

1 finding from 1 review

Long protocol vs three weeks before stimulation

Live birth or ongoing pregnancy · women undergoing pituitary suppression in assisted reproduction

Long protocol: administration of GnRHa for two showed no clear difference in live birth and ongoing pregnancies per woman randomised compared with three weeks before stimulation (low certainty).

1 finding from 1 review

Long protocol vs three weeks before stimulation

Clinical pregnancy rate · women undergoing pituitary suppression in assisted reproduction

Long protocol: administration of GnRHa for two showed no clear difference in clinical pregnancies per woman randomised compared with three weeks before stimulation (low certainty).

1 finding from 1 review

Long luteal phase protocol vs long follicular phase protocol

Live birth or ongoing pregnancy · women undergoing pituitary suppression in assisted reproduction

Long luteal phase protocol showed no clear difference in live birth and ongoing pregnancies per woman randomised compared with long follicular phase protocol (low certainty).

1 finding from 1 review

Long luteal phase protocol vs long follicular phase protocol

Clinical pregnancy rate · women undergoing pituitary suppression in assisted reproduction

Long luteal phase protocol showed no clear difference in clinical pregnancies per woman randomised compared with long follicular phase protocol (low certainty).

1 finding from 1 review

Long protocol continued GnRH agonist vs long protocol stop GnRH agonist

Ongoing pregnancy / live birth rate per woman · women undergoing pituitary suppression in assisted reproduction

Long protocol continued GnRH agonist showed no clear difference in live birth and ongoing pregnancies Number of live births or ongoing… compared with long protocol stop GnRH agonist (low certainty).

1 finding from 1 review

Intervention not reported

Early embryo transfer ‐ GM501 (specific) versus ISMI (other) · Women in assisted reproductive technology cycles (ART) receiving human pre‐implantation embryos in either early (cleavage stage transfer)…

It is very uncertain whether the intervention changes early embryo transfer ‐ GM501 (specific) versus ISMI (other) (very low certainty).

1 finding from 1 review

Intervention not reported

Early embryo transfer ‐ GM501 (specific) versus Sydney IVF (other) · Women in assisted reproductive technology cycles (ART) receiving human pre‐implantation embryos in either early (cleavage stage transfer)…

It is very uncertain whether the intervention changes early embryo transfer ‐ GM501 (specific) versus Sydney IVF (other) (very low certainty).

1 finding from 1 review