Suicide‐related behaviour · patients with preventing relapse and recurrence of a depressive disorder in children and adolescents
Medication showed no clear difference in suicide‐related behaviours compared with placebo (low certainty).
1 finding from 1 review
Total number of drop‐outs · patients with preventing relapse and recurrence of a depressive disorder in children and adolescents
Medication showed no clear difference in drop‐outs compared with placebo (moderate certainty).
1 finding from 1 review
Gambling symptom severity · patients with pathological and problem gambling
1 finding from 1 review
Gambling symptom severity · patients with pathological and problem gambling
1 finding from 1 review
Financial loss from gambling ‐ comparisons at 0 to 3 months post‐treatment Lower scores indicate reduced financial loss from gambling, and thus positive outcomes1 · patients with pathological and problem gambling
1 finding from 1 review
Frequency of gambling ‐ comparisons at 0 to 3 months post‐treatment Lower scores indicate reduced financial loss from gambling, and thus positive outcomes1 · patients with pathological and problem gambling
1 finding from 1 review
Financial loss from gambling ‐ comparisons at 0 to 3 months post‐treatment Lower scores indicate reduced financial loss from gambling, and thus positive outcomes1 · patients with pathological and problem gambling
1 finding from 1 review
Frequency of gambling ‐ comparisons at 0 to 3 months post‐treatment Lower scores indicate reduced severity of gambling, and thus positive outcomes1 · patients with pathological and problem gambling
1 finding from 1 review
Diagnoses of pathological gambling ‐ comparisons at 0 to 3 months post‐treatment Lower scores indicate reduced rates of pathological gambling, and thus positive outcomes1 · patients with pathological and problem gambling
CBT may leads to lower diagnoses of pathological gambling ‐ comparisons at 0 to 3 months… compared with control (low certainty).
1 finding from 1 review
Depression symptoms ‐ comparisons at 0 to 3 months post‐treatment Lower scores indicate reduced depression symptoms, and thus positive outcomes1 · patients with pathological and problem gambling
1 finding from 1 review
Anxiety · patients with pathological and problem gambling
1 finding from 1 review
Gambling symptom severity · patients with pathological and problem gambling
1 finding from 1 review
Financial loss from gambling ‐ comparisons at 0 to 3 months post‐treatment Lower scores indicate reduced financial loss from gambling, and thus positive outcomes1 · patients with pathological and problem gambling
1 finding from 1 review
Frequency of gambling ‐ comparisons at 0 to 3 months post‐treatment Lower scores indicate reduced financial loss from gambling, and thus positive outcomes1 · patients with pathological and problem gambling
1 finding from 1 review
Response rates Number of participants showing a reduction of at least 50% on the Hamilton Depression Rating Scale for Depression, the Montgomery‐Asberg Depression Rating Scale or any other depression scale · adults with Major Depressive Disorder
Amitriptyline probably leads to higher response to treatment At least 50% reduction of a depression scale… compared with placebo (moderate certainty).
1 finding from 1 review
Death due to suicide · adults with Major Depressive Disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · adults with Major Depressive Disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acceptability of treatment Drop‐out for any reason · adults with Major Depressive Disorder
It is very uncertain whether amitriptyline changes acceptability of treatment Drop‐out for any reason compared with placebo (very low certainty).
1 finding from 1 review
Adverse effects (drop‐outs due to adverse effects4) · adults with Major Depressive Disorder
Amitriptyline probably leads to higher overall tolerability Drop‐out due to adverse events compared with placebo (moderate certainty).
1 finding from 1 review