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Evidence found and GRADE certainty

4,860 questions · 64,864 findings · 4,913 reviews · Headline outcomes only

No studies found 13,869 · 21.4%GRADE not reported 3,491 · 5.4%Very low 16,300 · 25.1%Low 17,338 · 26.7%Moderate 10,900 · 16.8%High 2,966 · 4.6%

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SGLT2 inhibitors vs placebo

Hypoglycaemia requiring third‐party assistance median · people with diabetes and CKD

Sodium‐glucose co‐transporter protein 2 (SGLT2) inhibitors leads to lower hypoglycaemia requiring third‐party assistance median compared with placebo (high certainty).

1 finding from 1 review

wMel‐Wolbachia infected Aedes aegypti deployments vs no deployments

Prevalence of DENV infection (any severity, any phenotype)a · children and adults at risk of dengue infection

wMel‐Wolbachia infected Aedes aegypti deployments probably leads to lower prevalence of DENV infection (any severity, any phenotype)a compared with no deployments (moderate certainty).

1 finding from 1 review