Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

192 questions · 196 findings · 89 reviews

No studies found 31 · 15.8%GRADE not reported 18 · 9.2%Very low 68 · 34.7%Low 48 · 24.5%Moderate 24 · 12.2%High 7 · 3.6%

Probiotics vs placebo

Withdrawals due to adverse events · children with chronic constipation without a physical explanation

Probiotic showed no clear difference in withdrawals due to adverse events compared with placebo (low certainty).

1 finding from 1 review