Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

100 questions · 100 findings · 41 reviews

No studies found 31 · 31%GRADE not reported 4 · 4%Very low 34 · 34%Low 19 · 19%Moderate 10 · 10%High 2 · 2%

Percutaneous ethanol injection vs radiofrequency ablation

Serious adverse events (number of events) · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether percutaneous alcohol injection changes serious adverse events (number of events) compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Enhanced recovery protocol vs usual care

Serious adverse events (number) · people with major upper gastrointestinal, liver and pancreatic surgery

It is very uncertain whether enhanced recovery protocol changes serious adverse events (number) compared with standard care (very low certainty).

1 finding from 1 review

Chondroitin vs placebo

Number of serious adverse events · patients with osteoarthritis

Chondroitin probably leads to lower number of serious adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Routine abdominal drain vs No drain

Serious adverse events (number of events) · patients with laparoscopic cholecystectomy.

It is very uncertain whether routine abdominal drain changes serious adverse events (number of events) compared with 'no drain' (very low certainty).

1 finding from 1 review

Celecoxib vs tNSAIDs

Number of participants experiencing any serious adverse events · patients with osteoarthritis

It is very uncertain whether celecoxib changes number experiencing any serious adverse events compared with tNSAIDs (very low certainty).

1 finding from 1 review