Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

58 questions · 66 findings · 22 reviews · Infectious Diseases

No studies found 14 · 21.2%GRADE not reported 12 · 18.2%Very low 11 · 16.7%Low 15 · 22.7%Moderate 8 · 12.1%High 6 · 9.1%

Intervention not reported

Serious adverse events · ≥ 15‐year‐old people with late second stage human African gambiense trypanosomiasis (trypanosomes in blood or nymph node fluid and WBC >…

It is very uncertain whether the intervention changes serious adverse events (very low certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events · adults with P vivax malaria

It is very uncertain whether the intervention changes serious adverse events (very low certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events · adults and children with P vivax malaria

It is very uncertain whether the intervention changes serious adverse events (very low certainty).

1 finding from 1 review

Gatifloxacin‐containing 4‐month ATT regimens vs standard 6‐month ATT regimen

Serious adverse events · adults with drug‐sensitive pulmonary tuberculosis

Gatifloxacin‐containing 4‐month ATT regimens showed no clear difference in serious adverse events compared with standard 6‐month ATT regimens (moderate certainty).

1 finding from 1 review

Moxifloxacin‐containing 4‐month ATT regimens vs standard 6‐month ATT regimen

Serious adverse events · adults with drug‐sensitive pulmonary tuberculosis

Moxifloxacin‐containing 4‐month ATT regimens showed no clear difference in serious adverse events compared with standard 6‐month ATT regimen (moderate certainty).

1 finding from 1 review