Findings

What do systematic reviews say?

3,241 questions · 3,336 findings · 1,340 reviews

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No studies found 1,581 · 47.4%GRADE not reported 352 · 10.6%Very low 512 · 15.3%Low 509 · 15.3%Moderate 316 · 9.5%High 66 · 2%

Functional edentulism vs Individuals without functional edentulism

Poor oral health-related quality of life (OHRQoL) · Indians

Results were inconsistent and certainty was very low.

1 finding from 1 review

Impact of oral conditions on oral health-related quality of life among Indians- a systematic review and Meta-analysis. 2023 All outcomes
India
no estimate extracted
2 studies · 368 participants
Very low

Antibiotics vs no treatment or placebo on top of topical antibiotics

Health‐related quality of life ‐ unclear · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 101 participants
Very low

Doxycycline + SRP vs Metronidazole + SRP

Patient-reported quality of life changes · Adults with aggressive periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Long-term (≥ 1 year)
Included studies have not reported this outcome
Studies not reported
No studies found

Clindamycin + SRP vs Metronidazole + SRP

Patient-reported quality of life changes · Adults with aggressive periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Long-term (≥ 1 year)
Included studies have not reported this outcome
Studies not reported
No studies found

Clindamycin + SRP vs SRP

Patient-reported quality of life changes · Adults with aggressive periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Long-term (≥ 1 year)
Included studies have not reported this outcome
Studies not reported
No studies found

Tetracycline + SRP vs SRP

Patient-reported quality of life changes · Adults with aggressive periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Long-term (≥ 1 year)
Included studies have not reported this outcome
Studies not reported
No studies found

Doxycycline + SRP vs SRP

Patient-reported quality of life changes · Adults with aggressive periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Long-term (≥ 1 year)
Included studies have not reported this outcome
Studies not reported
No studies found

Amoxicillin + metronidazole + SRP vs SRP

Patient-reported quality of life changes · Adults with periodontitis (chronic and aggressive)

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Long-term (≥ 1 year)
Included studies have not reported this outcome
Studies not reported
No studies found

Amoxicillin + clavulanate + SRP vs SRP

Patient-reported quality of life changes · Adults with chronic periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Long-term (≥ 1 year)
Included studies have not reported this outcome
Studies not reported
No studies found

Helium thermal coagulator vs electrodiathermy

Quality of life (9 months) – EHP‐30 pain · endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 119 participants
Very low

Behavioural activation vs any comparator

Quality of life (medium term: 12 months) · depression in adults with non‐communicable diseases

1 finding from 1 review

Behavioural activation therapy for depression in adults with non‐communicable diseases 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Low

Clindamycin + SRP vs Doxycycline + SRP

Patient-reported quality of life changes · Adults with aggressive periodontitis

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Long-term (≥ 1 year)
Included studies have not reported this outcome
Studies not reported
No studies found

Azithromycin + SRP vs SRP

Patient-reported quality of life changes · Adults with periodontitis (chronic and aggressive)

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Long-term (≥ 1 year)
Included studies have not reported this outcome
Studies not reported
No studies found

Metronidazole + SRP vs SRP

Patient-reported quality of life changes · Adults with periodontitis (chronic and aggressive)

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Long-term (≥ 1 year)
Included studies have not reported this outcome
Studies not reported
No studies found

Intervention not reported

Patient satisfaction and quality of life · adults with PTS

The review found no eligible studies for this question.

1 finding from 1 review

Compression therapy for treating post‐thrombotic syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intravenous iron vs oral iron

QoL · people with preoperative anaemia awaiting major surgery

The review found no eligible studies for this question.

1 finding from 1 review

Iron therapy for preoperative anaemia 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise vs no exercise

Health‐related quality of life (HRQoL) · adult patients with an implantable cardioverter defibrillator

1 finding from 1 review

Exercise‐based cardiac rehabilitation for adult patients with an implantable cardioverter defibrillator 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 433 participants
Very low

Idebenone vs placebo

Improvements in quality of life measures · boys (aged 8 to 16 years old) with subclinical cardiomyopathy in DMD

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Eplerenone (25 mg daily) vs placebo

Improvements in quality of life measures · boys with DMD and left ventricular ejection fraction 45% or more

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Growth hormone (0.23 mg/kg/week for DMD and 0.07 mg/kg/week in BMD SC injection) vs placebo

Improvements in quality of life measures · people with DMD or BMD (ages not stated)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing and treating cardiac complications in Duchenne and Becker muscular dystrophy and X‐linked… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found