What do systematic reviews say?

Laparoscopic vs open appendectomy

• Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2009 participants
  Low

Educational intervention vs usual care or attention control

Educational interventions showed no clear difference in global quality of life (at the end of the educational intervention) compared with control (usual care or attention control) (low certainty).

• Educational interventions for the management of cancer‐related fatigue in adults 2016 · Cochrane Headline outcomes only
  MD 11.47
  2 studies · 477 participants
  Low

Single full-coverage metal-ceramic crown over composite core and post vs Direct adhesive composite restoration with post (conventional filling, no crown)

The review found no eligible studies for this question.

• Single crowns versus conventional fillings for the restoration of root‐filled teeth 2015 · Cochrane All outcomes
  This outcome was not reported nor measured by the study. The abstract confirms no evidence was available for any secondary outcome.
  Studies not reported
  No studies found

MHRV vs placebo

MHRV showed no clear difference in quality of life SGRQ Scale from 0 to 100 (0 on the scale is better) compared with placebo (moderate certainty).

• Dehumidifiers for chronic asthma 2013 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 100 participants
  Moderate

Minimal incision palatopharyngoplasty (MIPP) vs MIPP with additional individualised velopharyngeal surgery (pharyngeal flap or sphincter pharyngoplasty)

The review found no eligible studies for this question.

• Interventions for the management of submucous cleft palate 2008 · Cochrane All outcomes
  No data were available for this patient-reported outcome in the single included trial.
  0 studies
  No studies found

Face‐down positioning vs other positioning

It is very uncertain whether face‐down positioning changes quality of life assessments at 3 months or later (higher is favored) compared with other positioning (very low certainty).

• Face‐down positioning or posturing after pars plana vitrectomy for macula‐involving rhegmatogenous retinal detachments 2024 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 217 participants
  Very low

Care delivery and self‐management strategies vs usual care

Care delivery and self‐management strategies showed no clear difference in self‐perception of epilepsy on quality of life (PedsQL) at 3 months compared with usual care (low certainty).

• Care delivery and self‐management strategies for children with epilepsy 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 76 participants
  Low

Intervention not reported

• Specialist breast care nurses for support of women with breast cancer 2021 · Cochrane Headline outcomes only
  2009
  2 studies · 557 participants
  Moderate

Intervention not reported

The intervention may leads to lower cancer‐specific quality of life [assessed using a variety of scales, (low certainty).

• Specialist breast care nurses for support of women with breast cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 897 participants
  Low

Mobile stroke team vs general medical ward

• Organised inpatient (stroke unit) care for stroke: network meta‐analysis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 308 participants
  Very low

Acupuncture vs sham

• Acupuncture for chronic nonspecific low back pain 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 1068 participants
  Low

Personalised one-to-one OHA vs Routine one-to-one OHA

• One‐to‐one oral hygiene advice provided in a dental setting for oral health 2018 · Cochrane All outcomes
  Jonsson 2009 (OHQoL-UK oral health-related quality of life) and Ramsay 2018 (dental quality of life, oral hygiene self-efficacy); measured, not synthesised or GRADE-rated.
  2 studies
  GRADE not reported

Any form of one-to-one oral hygiene advice (OHA) vs No OHA

• One‐to‐one oral hygiene advice provided in a dental setting for oral health 2018 · Cochrane All outcomes
  Hoogstraten 1983 (dental knowledge, attitude, behaviour, fear of dental treatment) and Memarpour 2016 (parents' knowledge and performance regarding oral health); measured, not synthesised or GRADE-rated.
  2 studies
  GRADE not reported

Combination hearing aid vs hearing aid

The review found no eligible studies for this question.

• Sound therapy (using amplification devices and/or sound generators) for tinnitus 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Hearing aid vs sound generator

The review found no eligible studies for this question.

• Sound therapy (using amplification devices and/or sound generators) for tinnitus 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Enhanced one-to-one OHA vs Routine one-to-one OHA

• One‐to‐one oral hygiene advice provided in a dental setting for oral health 2018 · Cochrane All outcomes
  Hoogstraten 1983 (dental knowledge, attitude, behaviour, fear), Munster Halvari 2012 (multiple psychological measures: autonomy, motivation, perceived competence), Tedesco 1992 (theory of reasoned action variables);…
  3 studies
  GRADE not reported

Self-management (self-administered/self-monitored OHA) vs Professional OHA

• One‐to‐one oral hygiene advice provided in a dental setting for oral health 2018 · Cochrane All outcomes
  Aljafari 2017 reported child's dietary knowledge; measured, not synthesised or GRADE-rated.
  1 study
  GRADE not reported

Treatment of UI after radical: combinations of treatments vs no treatment

• Conservative management for postprostatectomy urinary incontinence 2015 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Prevention of UI after radical: one active treatment vs another active treatment (PFMT + penile vibration pre and post‐operation versus PFMT pre and post‐operation)

• Conservative management for postprostatectomy urinary incontinence 2015 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Prevention of UI after radical: one active treatment vs another active treatment (pre‐operative PFMT + electrical stimulation versus pre‐operative PFMT)

• Conservative management for postprostatectomy urinary incontinence 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 34 participants
  Very low