Findings

What do systematic reviews say?

305 questions · 313 findings · 111 reviews · Musculoskeletal

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No studies found 63 · 20.1%GRADE not reported 5 · 1.6%Very low 47 · 15%Low 111 · 35.5%Moderate 64 · 20.4%High 23 · 7.3%

Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone

Pain · children and young people with JIA

The review found no eligible studies for this question.

1 finding from 1 review

Methotrexate for juvenile idiopathic arthritis 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Methotrexate vs alternative disease‐modifying antirheumatic drugs

Pain · children and young people with JIA

The review found no eligible studies for this question.

1 finding from 1 review

Methotrexate for juvenile idiopathic arthritis 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prefabricated foot orthoses vs shoes

Pain · children with symptomatic flat feet

The review found no eligible studies for this question.

1 finding from 1 review

Foot orthoses for treating paediatric flat feet 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs placebo adjunctive therapies

Pain · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

Adjunctive therapies in addition to land‐based exercise therapy for osteoarthritis of the hip or knee 2022 · Cochrane Headline outcomes only
no estimate extracted
22 studies · 1428 participants
Low

Intervention not reported

Pain · adults aged ≥ 18 years with a diagnosis of glenohumeral osteoarthritis who have not responded to non‐operative treatments

1 finding from 1 review

Shoulder replacement surgery for osteoarthritis and rotator cuff tear arthropathy 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 92 participants
Low

Tramadol vs paracetamol

Pain · patients with osteoarthritis

1 finding from 1 review

Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Tramadol vs placebo

Pain · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 3972 participants
Moderate

Tramadol vs NSAIDs

Pain · patients with osteoarthritis

1 finding from 1 review

Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 952 participants
Moderate

Tramadol vs other opioids

Pain · patients with osteoarthritis

1 finding from 1 review

Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 411 participants
Moderate

Tramadol in combination with acetaminophen vs NSAIDs

Pain · patients with osteoarthritis

1 finding from 1 review

Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 226 participants
Moderate

Tramadol in combination with acetaminophen vs other opioids

Pain · patients with osteoarthritis

1 finding from 1 review

Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 130 participants
Low

Tramadol in combination with acetaminophen vs placebo

Pain · patients with osteoarthritis

1 finding from 1 review

Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 614 participants
Moderate

Exercise vs no intervention

Pain · adults with ankylosing spondylitis

1 finding from 1 review

Exercise programmes for ankylosing spondylitis 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 288 participants
Low

Exercise vs usual care

Pain · adults with ankylosing spondylitis

1 finding from 1 review

Exercise programmes for ankylosing spondylitis 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 911 participants
Moderate

Celecoxib vs placebo

Pain · patients with osteoarthritis

1 finding from 1 review

Celecoxib for osteoarthritis 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1622 participants
High

Celecoxib vs tNSAIDs

Pain · patients with osteoarthritis

1 finding from 1 review

Celecoxib for osteoarthritis 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1180 participants
Moderate

Intervention not reported

Pain · people following primary uncemented THA

The review found no eligible studies for this question.

1 finding from 1 review

Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Pain · people following primary uncemented THA

The review found no eligible studies for this question.

1 finding from 1 review

Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Pain · people following primary uncemented THA

The review found no eligible studies for this question.

1 finding from 1 review

Assistive devices, hip precautions, environmental modifications and training to prevent dislocation and improve… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Other types of high tibial osteotomy (aHTO) vs closing wedge high tibial osteotomy (CW‐HTO)

Pain · patients with osteoarthritis of the knee

1 finding from 1 review

Osteotomy for treating knee osteoarthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 216 participants
Low