Celecoxib vs tNSAIDs
It is very uncertain whether celecoxib changes number experiencing any serious adverse events compared with tNSAIDs (very low certainty).
- Peto OR 0.92 [0.66, 1.28]5 studies · 2404 participantsVery low
It is very uncertain whether celecoxib changes number experiencing any serious adverse events compared with tNSAIDs (very low certainty).
It is very uncertain whether celecoxib changes number experiencing any serious adverse events compared with placebo (very low certainty).
The review found no eligible studies for this question.
It is very uncertain whether tramadol alone changes number of participants experiencing any serious adverse events compared with NSAIDs (very low certainty).
It is very uncertain whether tramadol alone changes number of participants experiencing any serious adverse events compared with other opioids (very low certainty).
The review found no eligible studies for this question.
Tramadol alone may leads to higher number of participants experiencing any serious adverse events compared with placebo (low certainty).