Findings

What do systematic reviews say?

62 questions · 64 findings · 30 reviews

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No studies found 12 · 18.8%GRADE not reported 0 · 0%Very low 26 · 40.6%Low 11 · 17.2%Moderate 15 · 23.4%High 0 · 0%

Intervention not reported

Adverse events ‐ major infections Clinical events experienced by children during the 1 year period commencing at entry to the trial · 117 children with homozygous sickle cell (SS) disease

The intervention showed no clear difference in adverse events ‐ major infections Clinical events experienced by… (low certainty).

1 finding from 1 review

Folate supplementation in people with sickle cell disease 2018 · Cochrane Headline outcomes only
RR 0.89 [0.47, 1.66]
1 study · 115 participants
Low

Intervention not reported

Major adverse events** ‒short‐term (> 2 weeks but ≤ 3 months) Major adverse events provided as the proportion of patients reporting any untoward medical occurrence after an epidural injection with hospitalizations. · lumbosacral radicular pain

1 finding from 1 review

Epidural corticosteroid injections for lumbosacral radicular pain 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 160 participants
Moderate