What do systematic reviews say?

Exercise vs no exercise

• Exercise‐based cardiac rehabilitation in heart transplant recipients 2017 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 120 participants
  Moderate

Oat‐containing moisturisers vs vehicle or no moisturiser

• Emollients and moisturisers for eczema 2017 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 226 participants
  Low

Moisturisers vs vehicle, placebo or no moisturiser

• Emollients and moisturisers for eczema 2017 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 300 participants
  Low

Topical active treatment in combination with moisturiser vs topical active treatment alone

• Emollients and moisturisers for eczema 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 67 participants
  Low

Moisturisers vs no treatment (no moisturiser)

• Emollients and moisturisers for eczema 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 177 participants
  Low

Selenium (+LT4) vs placebo (+LT4)

The review found no eligible studies for this question.

• Selenium supplementation for Hashimoto's thyroiditis 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Supportive interventions for enhancing dietary intake vs comparators

• Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 4451 participants
  Low

Intervention not reported

The intervention showed no clear difference in health‐Related Quality of Life at least 20% improvement (moderate certainty).

• Methotrexate for treating rheumatoid arthritis 2014 · Cochrane Headline outcomes only
  RR 1.5 [1, 2.1]
  1 study · 263 participants
  Moderate

Compression bandages or stockings vs no compression stockings

• Compression bandages or stockings versus no compression for treating venous leg ulcers 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 859 participants
  Low

Surgery vs Pharmacological therapy

Surgery alone showed no clear difference in health‐related quality of life Mean AcroQoL score (0‐100) compared with pharmacological therapy alone (low certainty).

• Surgical and non‐surgical interventions for primary and salvage treatment of growth hormone‐secreting pituitary… 2024 · Cochrane Headline outcomes only
  MD 10
  1 study · 22 participants
  Low

Summary of findings table ‐ Cannabis vs placebo

• Cannabis and cannabinoids for symptomatic treatment for people with multiple sclerosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 1942 participants
  Low

Sinonasal debridement vs no debridement

• Sinonasal debridement versus no debridement for the postoperative care of patients undergoing endoscopic sinus surgery 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 58 participants
  Low

Pregabalin vs placebo

• Pregabalin for decreasing pancreatic pain in chronic pancreatitis 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 64 participants
  Moderate

Valgus knee brace vs no brace

• Braces and orthoses for treating osteoarthritis of the knee 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 117 participants
  Low

Lateral wedge insole vs neutral insole

• Braces and orthoses for treating osteoarthritis of the knee 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 179 participants
  Moderate

Intervention not reported

• Braces and orthoses for treating osteoarthritis of the knee 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 179 participants
  Moderate

Intervention not reported

It is very uncertain whether the intervention changes health‐related quality of life (Change in CRQ Fatigue) CRQ (very low certainty).

• Exercise training to improve exercise capacity and quality of life in people with non‐malignant dust‐related… 2015 · Cochrane Headline outcomes only
  MD 1 [0.11, 1.89]
  2 studies · 39 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes health‐related quality of life (Change in CRQ Mastery) CRQ (very low certainty).

• Exercise training to improve exercise capacity and quality of life in people with non‐malignant dust‐related… 2015 · Cochrane Headline outcomes only
  MD 1.51 [0.29, 2.72]
  2 studies · 39 participants
  Very low

Intervention not reported

• Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 212 participants
  Moderate

Summary of findings: Any alternative model of care vs usual care

Summary of findings: Any alternative model of care showed no clear difference in health‐related quality of life (mean difference) at longest compared with usual care (low certainty).

• Models for delivery and co‐ordination of primary or secondary health care (or both) to older adults living in aged… 2024 · Cochrane Headline outcomes only
  MD 0.016
  12 studies · 4016 participants
  Low