Findings

What do systematic reviews say?

8 questions · 9 findings · 2 reviews · Neonatal

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 4 · 44.4%Very low 0 · 0%Low 1 · 11.1%Moderate 4 · 44.4%High 0 · 0%

nHFV vs NCPAP

Death or chronic lung disease · newborn (term* and preterm) infants with respiratory distress for initial respiratory support

nHFV showed no clear difference in death or chronic lung disease compared with nCPAP used (low certainty).

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
RR 2.5 [0.52, 12.01]
1 study · 68 participants
Low

nHFV vs NIPPV or NIV

Death or chronic lung disease · preterm infants with respiratory distress for initial respiratory support

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

nHFV vs HFNC

Death or chronic lung disease · preterm infants with respiratory distress for initial respiratory support

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

nHFV vs NCPAP

Death or chronic lung disease · ventilated preterm infants with planned extubation

nHFV showed no clear difference in death or chronic lung disease compared with nCPAP (moderate certainty).

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
RR 0.9 [0.77, 1.06]
2 studies · 966 participants
Moderate

nHFV vs NIPPV or NIV

Death or chronic lung disease · ventilated preterm infants with planned extubation

nHFV showed no clear difference in death or chronic lung disease compared with nIPPV (moderate certainty).

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
RR 0.92 [0.79, 1.08]
3 studies · 1070 participants
Moderate

nHFV vs invasive respiratory therapy

Death or chronic lung disease · preterm infants with respiratory distress for initial respiratory support

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

nHFV vs nIPPV following failure of initial non‐invasive respiratory support

Death or chronic lung disease · ventilated preterm infants with failure of initial non‐invasive respiratory support

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Vitamin A vs no supplementation

Death or chronic lung disease · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A probably leads to lower death or chronic lung disease (oxygen use at 28 days) compared with no supplementation (moderate certainty).

2 findings from 1 review

Vitamin A supplementation to prevent mortality and short‐ and long‐term morbidity in very low birth weight infants 2016 · Cochrane Headline outcomes only
RR 0.93 [0.88, 0.99]
6 studies · 1165 participants
Moderate
Vitamin A supplementation to prevent mortality and short‐ and long‐term morbidity in very low birth weight infants 2016 · Cochrane Headline outcomes only
RR 0.92 [0.84, 1.01]
4 studies · 1089 participants
Moderate