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Evidence found and GRADE certainty

8 questions · 8 findings · 5 reviews · Infectious Diseases

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No studies found 1 · 12.5%GRADE not reported 0 · 0%Very low 3 · 37.5%Low 1 · 12.5%Moderate 3 · 37.5%High 0 · 0%

Moxifloxacin‐containing 4‐month ATT regimens vs standard 6‐month ATT regimen

Death from any cause · adults with drug‐sensitive pulmonary tuberculosis

Moxifloxacin‐containing 4‐month ATT regimens showed no clear difference in death from any cause compared with standard 6‐month ATT regimen (moderate certainty).

1 finding from 1 review

Gatifloxacin‐containing 4‐month ATT regimens vs standard 6‐month ATT regimen

Death from any cause · adults with drug‐sensitive pulmonary tuberculosis

Gatifloxacin‐containing 4‐month ATT regimens showed no clear difference in death from any cause compared with standard 6‐month ATT regimens (moderate certainty).

1 finding from 1 review

Fluoroquinolone substitution for ethambutol in a standard six month regimen vs standard regimen

Death from any cause · Patients with presumed drug‐sensitive TB

It is very uncertain whether fluoroquinolone substitution for ethambutol in a standard six month… changes death from any cause compared with standard regimen (very low certainty).

1 finding from 1 review

Fluoroquinolone substitution for isoniazid in a standard six month regimen vs standard regimen

Death from any cause · Patients with presumed drug‐sensitive TB

Fluoroquinolone substitution for isoniazid in a standard six month… showed no clear difference in death from any cause compared with standard regimen (low certainty).

1 finding from 1 review