Findings

What do systematic reviews say?

8 questions · 10 findings · 2 reviews · Airways

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No studies found 7 · 70%GRADE not reported 0 · 0%Very low 1 · 10%Low 1 · 10%Moderate 1 · 10%High 0 · 0%

Anxiolytics vs inactive control

Cardiovascular mortality · adults with central sleep apnoea associated with heart failure

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Methylxanthine derivatives vs inactive control

Cardiovascular mortality · adults with central sleep apnoea associated with heart failure

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Carbonic anhydrase inhibitors vs inactive control

Cardiovascular mortality · adults with central sleep apnoea associated with heart failure

It is very uncertain whether carbonic anhydrase inhibitors changes cardiovascular mortality compared with inactive control (very low certainty).

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
OR 0.21 [0.02, 2.48]
1 study · 18 participants
Very low

Hypnotics vs inactive control

Cardiovascular mortality · adults with primary central sleep apnoea

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP)

Cardiovascular mortality

The review found no eligible studies for this question.

2 findings from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adaptive servo ventilation (ASV) vs bilevel ventilation

Cardiovascular mortality

The review found no eligible studies for this question.

2 findings from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care

Cardiovascular mortality

Continuous positive airway pressure (CPAP) plus best supportive care showed no clear difference in cardiovascular mortality ‐ after 24 months Number of participants:… compared with best supportive care (low certainty).

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
RR 1.17 [0.68, 2.02]
Studies not reported
Low

Adaptive servo ventilation (ASV) plus best supportive care vs best supportive care alone or inactive control

Cardiovascular mortality

Adaptive servo ventilation (ASV) plus best supportive care probably leads to higher cardiovascular mortality ‐ up to 80 months Number of participants:… compared with best supportive care alone or inactive control (moderate certainty).

1 finding from 1 review

Non‐invasive positive pressure ventilation for central sleep apnoea in adults 2022 · Cochrane Headline outcomes only
RR 1.25 [1.04, 1.49]
Studies not reported
Moderate