Question · asked by 1 review

Carbonic anhydrase inhibitors vs inactive control: Cardiovascular mortality

It is very uncertain whether carbonic anhydrase inhibitors changes cardiovascular mortality compared with inactive control (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Carbonic anhydrase inhibitors vs inactive control
Cardiovascular mortality · adults with central sleep apnoea associated with heart failure
It is very uncertain whether carbonic anhydrase inhibitors changes cardiovascular mortality compared with inactive control (very low certainty).
Pharmacological treatment for central sleep apnoea in adults (2023) · Cochrane Headline outcomes only
OR 0.21 [0.02, 2.48]1 study · 18 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pharmacological treatment for central sleep apnoea in adults
2023 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.