Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

73 questions · 73 findings · 36 reviews · Headline outcomes only

No studies found 2 · 2.7%GRADE not reported 0 · 0%Very low 24 · 32.9%Low 23 · 31.5%Moderate 19 · 26%High 5 · 6.8%

Target of rapamycin inhibitors (TOR‐I) vs antimetabolites: primary outcomes

Death (all causes) · primary immunosuppression in kidney transplant recipients

Target of rapamycin inhibitors (TOR‐I) showed no clear difference in death (all causes) compared with antimetabolites: primary outcomes (moderate certainty).

1 finding from 1 review

Target of rapamycin inhibitors (TOR‐I) vs calcineurin inhibitors (CNI): main outcomes

Death (all causes) · primary immunosuppression in kidney transplant recipients

Target of rapamycin inhibitors (TOR‐I) showed no clear difference in death (all causes) compared with calcineurin inhibitors (CNI): main outcomes (moderate certainty).

1 finding from 1 review

Low vs higher dose target of rapamycin inhibitor (TOR‐ I): secondary outcomes

Death (all causes) · primary immunosuppression in kidney transplant recipients

Low showed no clear difference in death (all causes) compared with higher dose target of rapamycin inhibitor (TOR‐I): primary outcomes (moderate certainty).

1 finding from 1 review

Tenckhoff catheter with artificial curve at tunnel tract vs swan‐neck

Death (all causes) · preventing catheter‐related infections in chronic peritoneal dialysis patients

Tenckhoff catheter with artificial curve at tunnel tract showed no clear difference in death (all causes) compared with swan‐neck (low certainty).

1 finding from 1 review